Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 11/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | PLG | P00747 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | CHRND | Q07001 | 2/20 | 0.41 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.41 |
| ▸ | CHRNG | P07510 | 1/20 | 0.41 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571008 | 0.82 | PTPN1 (0.58) | PTPN1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7127958 | 0.80 | PTPN1 (0.60) | PTPN1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7569835 | 0.79 | PTPN1 (0.67) | PTPN1 | |
| SCHEMBL7127951 | 0.77 | CHRNB2 (0.47) | PTPN1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL6918308 | 0.75 | PTPN1 (0.69) | PTPN1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7066343 | 0.73 | PTPN1 (0.57) | PTPN1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL23086284 | 0.73 | PTPN1 (0.68) | PTPN1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7065637 | 0.73 | PTPN1 (0.51) | PTPN1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL21356920 | 0.70 | CHRNB2 (0.65) | PTPN1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL21356921 | 0.70 | CHRNB2 (0.65) | PTPN1CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020035137-A1 | Amino (oxo) acetic acid protein tyrosine phosphatase inhibitors | ABBOTT LABORATORIES | 2002-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020035137-A1 | Amino (oxo) acetic acid protein tyrosine phosphatase inhibitors | PPM1A, PTPRO, PTP4A1 | PTPN1 10/4885CHRNB2 4089/4885CHRNB4 4424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.