SCHEMBL522285

SCHEMBL522285

COC[C@H]1O[C@@H](n2cc(C)c(=O)[nH]c2=O)CC1O

nearest known ligand 0.72

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TK1 P04183 3/20 0.69
POLB P06746 1/20 0.68
TYMS P04818 1/20 0.60
BCHE P06276 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22943603 1.00 TK1 (0.69) TK1POLBTYMSBCHE
SCHEMBL135209 1.00 TK1 (0.69) TK1POLBTYMSBCHE
SCHEMBL17236294 1.00 TK1 (0.69) TK1POLBTYMSBCHE
SCHEMBL4198253 1.00 TK1 (0.69) TK1POLBTYMSBCHE
SCHEMBL17232081 1.00 TK1 (0.69) TK1POLBTYMSBCHE
SCHEMBL12918450 1.00 TK1 (0.69) TK1POLBTYMSBCHE
SCHEMBL8470853 0.91 TK1 (0.64) TK1POLBTYMSBCHE
SCHEMBL7571044 0.91 TK1 (0.66) TK1POLBTYMSBCHE
SCHEMBL4804983 0.91 POLB (0.68) TK1POLBTYMSBCHE
SCHEMBL6379335 0.91 POLB (0.68) TK1POLBTYMSBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12584168-B2 Sample preparation method OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-03-24 US disclosed
US-20260066042-A1 METHODS AND SYSTEMS FOR HIGH-THROUGHPUT MOLECULAR ANALYSIS OPENTRONS LABWORKS INC (US) 2026-03-05 US disclosed
US-20250313889-A1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2025-10-09 US disclosed
US-20240117337-A1 METHODS AND POLYNUCLEOTIDES FOR AMPLIFYING A TARGET POLYNUCLEOTIDE OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2024-04-11 US disclosed
US-20240076719-A9 METHOD OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2024-03-07 US disclosed
CN-117343990-A Method and kit for determining target polynucleotide and probe set 牛津纳米孔科技公开有限公司 2024-01-05 CN disclosed
US-20230295694-A1 METHOD OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2023-09-21 US disclosed
US-11725205-B2 Methods and polynucleotides for amplifying a target polynucleotide OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2023-08-15 US disclosed
US-20230250474-A1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2023-08-10 US disclosed
US-20230148152-A1 METHOD OF SYNTHESIZING SINGLE-STRANDED NUCLEOTIDE SEQUENCE, BLOCKED NUCLEOSIDE TRIPHOSPHATES AND RELATED METHODS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2023-05-11 US disclosed
EP-1385937-A1 DELIVERY OF POLYNUCLEOTIDE AGENTS TO THE CENTRAL NERVOUS SYSSTEM CHIRON CORPORATION (US) 2004-02-04 EP disclosed
US-6677445-B1 INCLUDING 5'-O-ALKYL NUCLEOTIDE, TWO BLOCKS OF SEVEN TO TWELVE PHOSPHODIESTER-LINKED 2'-O-ALKYL RIBONUCLEOTIDES, BLOCK OF FIVE TO TWELVE PHOSPHOROTHIOATE-LINKED DEOXYRIBONUCLEOTIDES, AND GROUP WHICH BLOCKS NUCLEASE ACTIVITY AT 3' END CHIRON CORPORATION 2004-01-13 US disclosed
EP-1373286-A2 LINKERS AND CO-COUPLING AGENTS FOR OPTIMIZATION OF OLIGONUCLEOTIDE SYNTHESIS AND PURIFICATION ON SOLID SUPPORT THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2004-01-02 EP disclosed
US-20030165434-A1 Delivery of polynucleotide agents to the central nervous system CHIRON CORPORATION 2003-09-04 US disclosed
US-20030120035-A1 Linkers and co-coupling agents for optimization of oligonucleotide synthesis and purification on solid supports THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2003-06-26 US disclosed
WO-2002086105-A1 DELIVERY OF POLYNUCLEOTIDE AGENTS TO THE CENTRAL NERVOUS SYSSTEM CHIRON CORPORATION (US) 2002-10-31 WO disclosed
WO-2002072791-A2 LINKERS AND CO-COUPLING AGENTS FOR OPTIMIZATION OF OLIGONUCLEOTIDE SYNTHESIS AND PURIFICATION ON SOLID SUPPORT THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2002-09-19 WO disclosed
US-20010044528-A1 Chimeric antisense oligonucleotides and cell transfecting formulations thereof INNIS MICHAEL A (US) 2001-11-22 US disclosed
EP-1144609-A2 CHIMERIC ANTISENSE OLIGONUCLEOTIDES AND CELL TRANSFECTING FORMULATIONS THEREOF CHIRON CORPORATION (US) 2001-10-17 EP disclosed
WO-2001016306-A2 CHIMERIC ANTISENSE OLIGONUCLEOTIDES AND CELL TRANSFECTING FORMULATIONS THEREOF CHIRON CORPORATION (US) 2001-03-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030120035-A1 Linkers and co-coupling agents for optimization of oligonucleotide synthesis and purification on solid supports PCNA, LIG4, DCLRE1A TK1 282/4885POLB 16/4885TYMS 222/4885
US-12584168-B2 Sample preparation method POLN, POLRMT, POLM TK1 472/4885POLB 4/4885TYMS 273/4885
US-20260066042-A1 METHODS AND SYSTEMS FOR HIGH-THROUGHPUT MOLECULAR ANALYSIS POLRMT, POLL, SARS1 TK1 1713/4885POLB 12/4885TYMS 179/4885
US-20230148152-A1 METHOD OF SYNTHESIZING SINGLE-STRANDED NUCLEOTIDE SEQUENCE, BLOCKED NUCLEOSIDE TRIPHOSPHATES AND RELATED METHODS RNGTT, NT5C3B, TYMP TK1 58/4885POLB 4/4885TYMS 7/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.