Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 5/20 | 0.74 |
| ▸ | PYGM | P11217 | 3/20 | 0.66 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.56 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.56 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.56 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.56 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.51 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TK1 | P04183 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27786493 | 1.00 | TK2 (0.74) | TK2PYGMSLC28A1SLC28A2SLC29A1 | |
| SCHEMBL13597474 | 1.00 | TK2 (0.74) | TK2PYGMSLC28A1SLC28A2SLC29A1 | |
| SCHEMBL13447935 | 1.00 | TK2 (0.74) | TK2PYGMSLC28A1SLC28A2SLC29A1 | |
| SCHEMBL13413052 | 1.00 | TK2 (0.74) | TK2PYGMSLC28A1SLC28A2SLC29A1 | |
| SCHEMBL1532596 | 1.00 | TK2 (0.74) | TK2PYGMSLC28A1SLC28A2SLC29A1 | |
| SCHEMBL1627679 | 1.00 | TK2 (0.74) | TK2PYGMSLC28A1SLC28A2SLC29A1 | |
| SCHEMBL23083301 | 1.00 | TK2 (0.74) | TK2PYGMSLC28A1SLC28A2SLC29A1 | |
| SCHEMBL13252708 | 1.00 | TK2 (0.74) | TK2PYGMSLC28A1SLC28A2SLC29A1 | |
| SCHEMBL2587226 | 1.00 | TK2 (0.74) | TK2PYGMSLC28A1SLC28A2SLC29A1 | |
| SCHEMBL1532595 | 1.00 | TK2 (0.74) | TK2PYGMSLC28A1SLC28A2SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020169140-A1 | Combination therapy for reduction of toxicity of chemotherapeutic agents | HOLLIS-EDEN PHARMACEUTICALS, INC. | 2002-11-14 | — | — | US | disclosed |
| EP-0074101-A1 | 1-Beta-D-arabinofuranosyl-(E)-5-(2-halogenovinyl) uracil-5'-phosphate, preparation thereof and use thereof | Yamasa Shoyu Kabushiki Kaisha (JP) | 1983-03-16 | — | — | EP | disclosed |