SCHEMBL1532595

SCHEMBL1532595

C=Cc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]c1=O

nearest known ligand 0.74

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TK2 O00142 5/20 0.74
PYGM P11217 3/20 0.66
SLC28A1 O00337 1/20 0.56
SLC28A2 O43868 1/20 0.56
SLC29A1 Q99808 1/20 0.56
SLC28A3 Q9HAS3 1/20 0.56
P2RY2 P41231 2/20 0.51
DNPH1 O43598 1/20 0.49
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
TSHR P16473 1/20 0.47
TK1 P04183 1/20 0.47
BLM P54132 1/20 0.47
PMP22 Q01453 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27786493 1.00 TK2 (0.74) TK2PYGMSLC28A1SLC28A2SLC29A1
SCHEMBL13597474 1.00 TK2 (0.74) TK2PYGMSLC28A1SLC28A2SLC29A1
SCHEMBL13447935 1.00 TK2 (0.74) TK2PYGMSLC28A1SLC28A2SLC29A1
SCHEMBL13413052 1.00 TK2 (0.74) TK2PYGMSLC28A1SLC28A2SLC29A1
SCHEMBL1532596 1.00 TK2 (0.74) TK2PYGMSLC28A1SLC28A2SLC29A1
SCHEMBL1627679 1.00 TK2 (0.74) TK2PYGMSLC28A1SLC28A2SLC29A1
SCHEMBL23083301 1.00 TK2 (0.74) TK2PYGMSLC28A1SLC28A2SLC29A1
SCHEMBL13252708 1.00 TK2 (0.74) TK2PYGMSLC28A1SLC28A2SLC29A1
SCHEMBL2587226 1.00 TK2 (0.74) TK2PYGMSLC28A1SLC28A2SLC29A1
SCHEMBL7571099 1.00 TK2 (0.74) TK2PYGMSLC28A1SLC28A2SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250127774-A1 COMPOUNDS FOR LABELLING NUCLEIC ACID AND USES THEREOF THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIV (CA) 2025-04-24 US claimed
CN-119325467-A Compounds for labeling nucleic acids and uses thereof 皇家学习促进学会/麦吉尔大学 2025-01-17 CN claimed
EP-4476206-A1 COMPOUNDS FOR LABELLING NUCLEIC ACID AND USES THEREOF The Royal Institution for the Advancement of Learning / McGill University (CA) 2024-12-18 EP claimed
WO-2023150867-A1 COMPOUNDS FOR LABELLING NUCLEIC ACID AND USES THEREOF THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) 2023-08-17 WO claimed
JP-4651942-B2 2011-03-16 JP claimed
US-20100168052-A1 Treatment of EBV and KHSV Infection and Associated Abnormal Cellular Proliferation PHARMASSET, INC. (US) 2010-07-01 US claimed
US-20070197462-A1 Treatment of EBV and KHSV infection and associated abnormal cellular proliferation PHARMASSET, INC. (US) 2007-08-23 US claimed
EP-1569658-A4 TREATMENT OF EBV AND KHSV INFECTION AND ASSOCIATED ABNORMAL CELLULAR PROLIFERATION PHARMASSETT LTD (BB) 2007-05-30 EP claimed
JP-2005528334-A 2005-09-22 JP claimed
EP-1569658-A2 TREATMENT OF EBV AND KHSV INFECTION AND ASSOCIATED ABNORMAL CELLULAR PROLIFERATION Pharmassett Ltd. (BB) 2005-09-07 EP claimed
US-20030176392-A1 Administering 5-substituted uracil-nucleosides or its pharmaceutically acceptable salt or prodrug for therapy of infected with Epstein-Barr virus or Kaposi's sarcoma-associated herpes (\"KHSV\") EMORY UNIVERSITY 2003-09-18 US claimed
WO-2003053360-A2 TREATMENT OF EBV AND KHSV INFECTION AND ASSOCIATED ABNORMAL CELLULAR PROLIFERATION PHARMASSETT LTD. (BB) 2003-07-03 WO claimed
EP-3760734-B1 NUCLEIC ACID MODIFICATION AND IDENTIFICATION METHOD IMBA INST MOLEKULARE BIOTECH (AT) 2025-08-20 EP disclosed
US-20250127774-A1 COMPOUNDS FOR LABELLING NUCLEIC ACID AND USES THEREOF THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIV (CA) 2025-04-24 US disclosed
CN-119325467-A Compounds for labeling nucleic acids and uses thereof 皇家学习促进学会/麦吉尔大学 2025-01-17 CN disclosed
EP-4476206-A1 COMPOUNDS FOR LABELLING NUCLEIC ACID AND USES THEREOF The Royal Institution for the Advancement of Learning / McGill University (CA) 2024-12-18 EP disclosed
EP-0702675-A1 METHOD FOR PALLADIUM CATALYZED CARBON-CARBON COUPLING AND PRODUCTS WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) 1996-03-27 EP disclosed
EP-0702675-A4 METHOD FOR PALLADIUM CATALYZED CARBON-CARBON COUPLING AND PRODUCTS UNIV WASHINGTON (US) 1996-02-02 EP disclosed
US-5428149-A Reacting vinyl and aryl stannanes with 2'-deoxy-5-halo-uridine WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) 1995-06-27 US disclosed
WO-1994029279-A1 METHOD FOR PALLADIUM CATALYZED CARBON-CARBON COUPLING AND PRODUCTS WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) 1994-12-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030176392-A1 Administering 5-substituted uracil-nucleosides or its pharmaceutically acceptable salt or prodrug for therapy of infected with Epstein-Barr virus or Kaposi's sarcoma-associated herpes (\"KHSV\") UMPS, UNG, TYMP TK2 90/4885PYGM 1497/4885SLC28A1 19/4885
US-20070197462-A1 Treatment of EBV and KHSV infection and associated abnormal cellular proliferation UMPS, ENTPD5, TK1 TK2 54/4885PYGM 2479/4885SLC28A1 33/4885
US-20250127774-A1 COMPOUNDS FOR LABELLING NUCLEIC ACID AND USES THEREOF POLRMT, NSUN2, NSUN3 TK2 56/4885PYGM 3534/4885SLC28A1 80/4885
US-20100168052-A1 Treatment of EBV and KHSV Infection and Associated Abnormal Cellular Proliferation UMPS, ENTPD5, TK1 TK2 54/4885PYGM 2479/4885SLC28A1 33/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.