Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 2/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.48 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PTPRA | P18433 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | BRD2 | P25440 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27285183 | 0.84 | PPARG (0.43) | PTGER1PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL22873307 | 0.81 | TRPM8 (0.48) | MAPTKDM4EPOLBL3MBTL1CYP1A2 | |
| SCHEMBL31276090 | 0.81 | TRPM8 (0.48) | MAPTKDM4EPOLBL3MBTL1CYP1A2 | |
| SCHEMBL23189270 | 0.78 | KMT2A (0.71) | PTGER1PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL3149585 | 0.78 | KMT2A (0.71) | PTGER1PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL17051298 | 0.78 | KMT2A (0.51) | PTGER1PTGER4PTGER3PTGER2KMT2A | |
| Bromide SCHEMBL27746577 | 0.77 | KDM4E (0.41) | MAPTKDM4EPOLBL3MBTL1CYP1A2 | |
| SCHEMBL8520662 | 0.77 | APAF1 (0.59) | PTGER1PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL1177969 | 0.76 | KDM4E (0.53) | PTGER1PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL4777973 | 0.76 | KDM4E (0.50) | MAPTKDM4EPOLBL3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743317-B1 | Metallocenes comprising a heterocycle and catalysts containing them | BASELL POLYOLEFINE GMBH (DE) | 2002-08-28 | — | — | EP | disclosed |
| US-5840947-A | Organometallic compound | TARGOR GMBH (DE) | 1998-11-24 | — | — | US | disclosed |
| EP-0743317-A2 | Metallocenes comprising a heterocycle and catalysts containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-11-20 | — | — | EP | disclosed |