Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 8/20 | 0.67 |
| ▸ | PKLR | P30613 | 3/20 | 0.62 |
| ▸ | CDK1 | P06493 | 1/20 | 0.58 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.58 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.58 |
| ▸ | CDK2 | P24941 | 1/20 | 0.58 |
| ▸ | CDK7 | P50613 | 1/20 | 0.58 |
| ▸ | CCNH | P51946 | 1/20 | 0.58 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | BRD1 | O95696 | 1/20 | 0.55 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10361762 | 0.87 | MAPT (0.65) | PKMPKLRCDK1CCNB1CCNA2 | |
| SCHEMBL23109373 | 0.87 | PKM (0.62) | PKMPKLRTP53GAALMNA | |
| SCHEMBL1250772 | 0.83 | VCAM1 (0.62) | PKMPKLRGAALMNAMAPT | |
| SCHEMBL7571133 | 0.81 | MAPT (0.63) | CDK1CCNB1CCNA2CDK2CDK7 | |
| SCHEMBL14403177 | 0.80 | PKM (0.71) | PKMPKLRTP53GAALMNA | |
| SCHEMBL7571166 | 0.80 | MAPT (0.80) | LMNAMAPTALDH1A1PGR | |
| SCHEMBL30532923 | 0.80 | PKM (0.71) | PKMPKLRTP53GAALMNA | |
| SCHEMBL31589145 | 0.79 | CDK1 (0.60) | PKMPKLRCDK1CCNB1CCNA2 | |
| SCHEMBL1248805 | 0.78 | PKM (0.62) | PKMPKLRTP53GAALMNA | |
| SCHEMBL7573977 | 0.78 | PKM (0.64) | PKMPKLRTP53GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |