Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 2/20 | 0.52 |
| ▸ | EDNRB | P24530 | 1/20 | 0.52 |
| ▸ | EDNRA | P25101 | 1/20 | 0.52 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | KIT | P10721 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15045213 | 0.84 | KMT2A (0.71) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL7588947 | 0.83 | KMT2A (0.57) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL7577405 | 0.83 | PTPRC (0.60) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL21693592 | 0.82 | KMT2A (0.73) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL13933287 | 0.80 | HSD17B2 (0.66) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL15045212 | 0.79 | KMT2A (0.69) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL2665022 | 0.79 | KMT2A (0.73) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL15045384 | 0.79 | KMT2A (0.60) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL7571567 | 0.78 | HSD17B2 (0.63) | KMT2AMEN1ALDH1A1MAPTHDAC1 | |
| SCHEMBL95092 | 0.78 | KMT2A (0.68) | KMT2AMEN1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |