Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | EDNRA | P25101 | 2/20 | 0.56 |
| ▸ | EDNRB | P24530 | 1/20 | 0.56 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | FBP1 | P09467 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7594368 | 0.83 | WDR5 (0.60) | KMT2AMEN1EDNRAEDNRB | |
| SCHEMBL7571512 | 0.83 | KMT2A (0.60) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL5956125 | 0.81 | ALDH1A1 (0.59) | ALDH1A1MAPTLMNAHTT | |
| SCHEMBL28636424 | 0.80 | KMT2A (0.65) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL9266314 | 0.78 | PTGES2 (0.70) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL7901144 | 0.78 | KMT2A (0.62) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL15045213 | 0.77 | KMT2A (0.71) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL7591899 | 0.76 | KMT2A (0.61) | KMT2AMEN1LMNASLC40A1HDAC1 | |
| SCHEMBL6920158 | 0.76 | KMT2A (0.69) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL25495354 | 0.76 | EDNRA (0.55) | KMT2AALDH1A1MEN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |