Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Itaconate SCHEMBL2641437 | 0.95 | HSD17B10 (0.60) | HSD17B10ALOX15MAPTCACNA1BAPBA1 | |
| 1,1-Dichloroethene SCHEMBL1818423 | 0.84 | TSHR (0.46) | HSD17B10MAPTCACNA1BAPBA1TSHR | |
| Itaconate SCHEMBL6226414 | 0.84 | HSD17B10 (0.55) | HSD17B10ALOX15TSHRALDH1A1TP53 | |
| SCHEMBL10939902 | 0.83 | HSD17B10 (0.44) | HSD17B10ALOX15MAPTCACNA1BAPBA1 | |
| Itaconate SCHEMBL7747257 | 0.83 | HSD17B10 (0.53) | HSD17B10ALOX15TSHRALDH1A1TP53 | |
| Malonic Acid SCHEMBL8735862 | 0.82 | MAPT (0.48) | HSD17B10ALOX15MAPTCACNA1BAPBA1 | |
| Itaconate SCHEMBL218838 | 0.81 | HSD17B10 (0.60) | HSD17B10ALOX15TSHRALDH1A1TP53 | |
| Itaconate SCHEMBL6556844 | 0.79 | TSHR (0.63) | HSD17B10ALOX15MAPTTSHRALDH1A1 | |
| Itaconate SCHEMBL8029816 | 0.79 | ALOX15 (0.87) | HSD17B10ALOX15TSHRALDH1A1MAPK1 | |
| Itaconate SCHEMBL6913753 | 0.78 | HSD17B10 (0.60) | HSD17B10ALOX15TSHRALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869391-B1 | Heat-developable photographic materials | FUJI PHOTO FILM CO LTD (JP) | 2002-06-26 | — | — | EP | disclosed |
| US-6027872-A | SUPPORT COATED WITH PHOTOSENSITIVE SILVER HALIDE, ORGANIC SILVER SALT, REDUCING AGENT AND A DISULFIDE COMPOUND FOR IMPROVED INFRARED SENSITIVITY | FUJI PHOTO FILM CO., LTD. (JP) | 2000-02-22 | — | — | US | disclosed |
| US-6025122-A | MATERIAL COMPRISING REDUCIBLE SILVER SALT, REDUCING AGENT, CONTRAST ENHANCER, BINDER, THIOSULFONIC ACID OR ESTER COMPOUND; ULTRAHIGH CONTRAST, LOW FOG, MINIMIZED VARIATION OF PHOTOGRAPHIC CHARACTERISTICS WITH HEAT DEVELOPMENT | FUJI PHOTO FILM CO., LTD. (JP) | 2000-02-15 | — | — | US | disclosed |
| EP-0869391-A1 | Heat-developable photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1998-10-07 | — | — | EP | disclosed |
| US-5747237-A | SUPPORT WITH PREFOGGED DIRECT POSITIVES EMULSION LAYER WITH SILVER HALIDE SOLVENT AND GRAINS, RHODIUM AND RUTHENIUM SALTS | FUJI PHOTO FILM CO., LTD. (JP) | 1998-05-05 | — | — | US | disclosed |
| US-5593811-A | Multilayer, sheet-like, photosensitive recording material for the production of printing plates | BASF LACKE+FARBEN AKTIENGESELLSCHAFT (DE) | 1997-01-14 | — | — | US | disclosed |
| EP-0340772-B1 | POLYESTER FILM USEFUL AS A SUPPORT FOR BRAILLE PRINTING | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-08-26 | — | — | EP | disclosed |
| US-5061611-A | Polyester support; hydrophobic vinylidene chloride copolymer | KONICA CORPORATION (JP) | 1991-10-29 | — | — | US | disclosed |
| US-5035981-A | Having a top layer of high-strength, transparent, soluble or swellable polymer containing an antistatic agent of an ethoxylated amine or amide; exposure; development | BASF AKTIENGESELLSCHAFT (DE) | 1991-07-30 | — | — | US | disclosed |
| US-4946758-A | RELIEF IMAGE FORMING LAYER; HIGH TENSILE STRENGTH POLYMER AND COVERING | BASF AKTIENGESELLSCHAFT (DE) | 1990-08-07 | — | — | US | disclosed |
| EP-0340772-A1 | Polyester film useful as a support for braille printing | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-11-08 | — | — | EP | disclosed |
| US-4002802-A | COATING A THERMOPLASTIC RESIN FILM WITH AN AQUEOUS POLYMERIC EMULSION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-01-11 | — | — | US | disclosed |