Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571893 | 0.89 | KMT2A (0.47) | NFE2L2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7571889 | 0.89 | KMT2A (0.47) | NFE2L2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7579581 | 0.87 | SLC2A1 (0.40) | NFE2L2ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7579658 | 0.85 | NFE2L2 (0.53) | NFE2L2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7575413 | 0.81 | NFE2L2 (0.35) | NFE2L2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7575405 | 0.81 | NFE2L2 (0.35) | NFE2L2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7572816 | 0.80 | CHRM5 (0.42) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7572820 | 0.80 | CHRM5 (0.42) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7572958 | 0.80 | KMT2A (0.50) | NFE2L2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7582214 | 0.80 | MEN1 (0.55) | NFE2L2ALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810199-B1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5756769-A | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0810199-A1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |