Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7575413 | 1.00 | NFE2L2 (0.35) | NFE2L2NPC1CASP3SENP8SENP7 | |
| SCHEMBL7580233 | 0.86 | PARP15 (0.38) | NPC1GAATDP1LMNAALDH1A1 | |
| SCHEMBL7580227 | 0.86 | PARP15 (0.38) | NPC1GAATDP1LMNAALDH1A1 | |
| SCHEMBL7572816 | 0.85 | CHRM5 (0.42) | NPC1CASP3SENP8SENP7SENP6 | |
| SCHEMBL7572820 | 0.85 | CHRM5 (0.42) | NPC1CASP3SENP8SENP7SENP6 | |
| SCHEMBL7572455 | 0.85 | SMN1; SMN2 (0.35) | L3MBTL1CA2LMNAALDH1A1MEN1 | |
| SCHEMBL7572457 | 0.85 | SMN1; SMN2 (0.35) | L3MBTL1CA2LMNAALDH1A1MEN1 | |
| SCHEMBL7574476 | 0.81 | MAPT (0.36) | NPC1GAAL3MBTL1TDP1LMNA | |
| SCHEMBL7574480 | 0.81 | MAPT (0.36) | NPC1GAAL3MBTL1TDP1LMNA | |
| SCHEMBL7579581 | 0.81 | SLC2A1 (0.40) | NFE2L2NPC1GAAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810199-B1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5756769-A | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0810199-A1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |