Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 12/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571999 | 0.88 | P2RX7 (0.70) | P2RX7EPHX2ADORA2A | |
| SCHEMBL7571551 | 0.81 | P2RX7 (0.66) | P2RX7EPHX2 | |
| SCHEMBL7571956 | 0.78 | P2RX7 (1.00) | P2RX7EPHX2 | |
| SCHEMBL14160432 | 0.77 | P2RX7 (0.71) | P2RX7EPHX2ADORA2A | |
| SCHEMBL7576509 | 0.75 | P2RX7 (0.77) | P2RX7EPHX2ADORA2A | |
| SCHEMBL13753145 | 0.75 | CNR2 (0.60) | EPHX2 | |
| SCHEMBL13753076 | 0.74 | CNR2 (0.48) | EPHX2 | |
| SCHEMBL19524976 | 0.72 | ITGA4 (0.46) | P2RX7 | |
| SCHEMBL7571850 | 0.72 | P2RX7 (0.74) | P2RX7 | |
| SCHEMBL3745042 | 0.71 | P2RX7 (0.48) | P2RX7EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036059-B1 | ADAMANTANE DERIVATIVES | ASTRAZENECA UK LTD (GB) | 2002-09-18 | — | — | EP | claimed |
| EP-1036059-B1 | ADAMANTANE DERIVATIVES | ASTRAZENECA UK LTD (GB) | 2002-09-18 | — | — | EP | disclosed |