Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18615253 | 0.81 | ALDH1A1 (0.33) | ALDH1A1HTTHPGDAPOBEC3GCYP2C19 | |
| SCHEMBL23126460 | 0.81 | ALDH1A1 (0.33) | ALDH1A1HTTHPGDAPOBEC3G | |
| SCHEMBL7567303 | 0.80 | SLC2A1 (0.37) | MAPTKDM4E | |
| SCHEMBL19091956 | 0.78 | ALDH1A1 (0.30) | ALDH1A1HPGDAPOBEC3G | |
| SCHEMBL11151001 | 0.78 | NR1H4 (0.39) | ALDH1A1HTTLMNAHPGDKMT2A | |
| SCHEMBL18615221 | 0.75 | DRD2 (0.37) | ALDH1A1LMNASLC18A3MEN1KMT2A | |
| SCHEMBL18615067 | 0.73 | CHRM2 (0.31) | ALDH1A1HTTHPGD | |
| SCHEMBL18629854 | 0.73 | — | — | |
| SCHEMBL12269802 | 0.73 | ALDH1A1 (0.58) | ALDH1A1LMNAHPGDAPOBEC3GMEN1 | |
| SCHEMBL24157929 | 0.72 | ESR1 (0.40) | PKMALDH1A1HTTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384282-B2 | CATALYST IS REACTION PRODUCT OF GROUP 8 METAL AND LIGAND | YALE UNIVERSITY | 2002-05-07 | — | — | US | disclosed |
| US-20020016509-A1 | Transition metal-catalyzed process for addition of amines to carbon-carbon double bonds | YALE UNIVERSITY | 2002-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020016509-A1 | Transition metal-catalyzed process for addition of amines to carbon-carbon double bonds | COASY, CMA1, ATIC | PKM 1955/4885ALDH1A1 193/4885HTT 4702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.