Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 2/20 | 0.41 |
| ▸ | FNTB | P49356 | 2/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21020725 | 0.86 | PLA2G7 (0.57) | PLA2G7ARTSHRKDM4EALDH1A1 | |
| SCHEMBL27385133 | 0.86 | TSHR (0.47) | PLA2G7ARTSHRKDM4EALDH1A1 | |
| SCHEMBL5901013 | 0.82 | ALDH1A1 (0.48) | PLA2G7ARTSHRKDM4EALDH1A1 | |
| SCHEMBL21036117 | 0.81 | ALDH1A1 (0.46) | PLA2G7ARTSHRKDM4EALDH1A1 | |
| SCHEMBL18406703 | 0.81 | FNTA (0.50) | ARTSHRLRRK2FNTAFNTB | |
| SCHEMBL2650355 | 0.79 | CYP11B1 (0.46) | ARTSHRKDM4EALDH1A1USP2 | |
| SCHEMBL1472952 | 0.79 | TSHR (0.67) | ARTSHRKDM4EALDH1A1LMNA | |
| SCHEMBL10094651 | 0.79 | PLA2G7 (0.71) | PLA2G7TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL21899505 | 0.79 | ALDH1A1 (0.42) | PLA2G7ARTSHRKDM4EALDH1A1 | |
| SCHEMBL4229761 | 0.77 | PTPRC (0.61) | PLA2G7TSHRKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020019527-A1 | Substituted phenyl farnesyltransferase inhibitors | ABBOTT LABORATORIES | 2002-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019527-A1 | Substituted phenyl farnesyltransferase inhibitors | FNTA, FNTB, SLC10A1 | PLA2G7 256/4885AR 4525/4885TSHR 3465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.