Tetrylammonium

Tetrylammonium

SCHEMBL7572283

CC[N+](CC)(CC)CC.COC(=O)[O-]

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.44
NFKB1 P19838 1/20 0.44
KCNA1 Q09470 1/20 0.44
KDM4E B2RXH2 1/20 0.42
PMP22 Q01453 1/20 0.42
ATM Q13315 1/20 0.42
BBOX1 O75936 4/20 0.33
FFAR3 O14843 2/20 0.33
HDAC3 O15379 2/20 0.33
HDAC1 Q13547 2/20 0.33
HDAC2 Q92769 2/20 0.33
HDAC8 Q9BY41 2/20 0.33
CA4 P22748 2/20 0.33
ALDH1A1 P00352 1/20 0.33
MGAM O43451 2/20 0.32
GAA P10253 2/20 0.32
SI P14410 2/20 0.32
MGAM2 Q2M2H8 2/20 0.32
HSD17B10 Q99714 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrylammonium SCHEMBL29047699 0.83 TSHR (0.44) TSHRNFKB1KCNA1KDM4EPMP22
SCHEMBL10410042 0.83 BBOX1 (0.38) TSHRNFKB1BBOX1FFAR3HDAC3
Tetrylammonium SCHEMBL15632811 0.82 TSHR (0.38) TSHRNFKB1KCNA1KDM4EPMP22
Tetrylammonium SCHEMBL168440 0.82 TSHR (0.57) TSHRNFKB1KCNA1KDM4EPMP22
SCHEMBL10641701 0.81 BBOX1 (0.46) TSHRNFKB1BBOX1FFAR3HDAC3
SCHEMBL2229655 0.81 BBOX1 (0.46) TSHRNFKB1BBOX1FFAR3HDAC3
Tetrylammonium SCHEMBL4773294 0.80 MGAM (0.42) TSHRNFKB1KCNA1KDM4EPMP22
Tetrylammonium SCHEMBL4772080 0.80 CA4 (0.59) TSHRNFKB1KCNA1KDM4EPMP22
Tetrylammonium SCHEMBL9004237 0.80 TSHR (0.47) TSHRNFKB1KCNA1KDM4EPMP22
Tetrylammonium SCHEMBL18144308 0.79 TSHR (0.53) TSHRNFKB1KCNA1KDM4EPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2977395-A1 HIGHLY REACTIVE, POLYURETHANE COMPOSITIONS CONTAINING URETDIONE GROUPS WHICH CONTAIN THE CARBONATE SALTS Evonik Degussa GmbH (DE) 2016-01-27 EP claimed
US-20160017179-A1 HIGH-REACTIVITY POLYURETHANE COMPOSITIONS CONTAINING URETDIONE GROUPS AND COMPRISING CARBONATE SALTS EVONIK DEGUSSA GMBH (DE) 2016-01-21 US claimed
EP-2977395-A1 HIGHLY REACTIVE, POLYURETHANE COMPOSITIONS CONTAINING URETDIONE GROUPS WHICH CONTAIN THE CARBONATE SALTS Evonik Degussa GmbH (DE) 2016-01-27 EP disclosed
US-20160017179-A1 HIGH-REACTIVITY POLYURETHANE COMPOSITIONS CONTAINING URETDIONE GROUPS AND COMPRISING CARBONATE SALTS EVONIK DEGUSSA GMBH (DE) 2016-01-21 US disclosed
EP-0999206-B1 Process for producing alpha cyano acetic acid esters BASF AG (DE) 2002-09-18 EP disclosed
US-6130347-A REACTING MONOCHLOROACETIC ESTER WITH HYDROGEN CYANIDE IN BASE PRESENCE; CYANATION BASF AKTIENGESELLSCHAFT (DE) 2000-10-10 US disclosed
EP-0999206-A1 Process for producing alpha cyano acetic acid esters BASF AKTIENGESELLSCHAFT (DE) 2000-05-10 EP disclosed
EP-0671384-B1 Process for the preparation of 3-cyano-3,5,5,-trimethyl-cyclohexanone BASF AG (DE) 1999-11-03 EP disclosed
US-5516928-A REACTION OF ISOPHORONE AND HYDROGEN CYANIDE USING QUATERNARY AMMONIUM CATALYST BASF AKTIENGESELLSCHAFT (DE) 1996-05-14 US disclosed
EP-0671384-A1 Process for the preparation of 3-cyano-3,5,5,-trimethyl-cyclohexanone BASF AKTIENGESELLSCHAFT (DE) 1995-09-13 EP disclosed
US-4776929-A Process for production of quaternary ammonium hydroxides MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1988-10-11 US disclosed