Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572273 | 0.80 | DHFR (0.43) | USP7DHFR | |
| SCHEMBL6555136 | 0.79 | DHFR (0.50) | DHFR | |
| SCHEMBL6557155 | 0.77 | DHFR (0.54) | DHFR | |
| SCHEMBL6555063 | 0.74 | DHFR (0.48) | DHFR | |
| SCHEMBL6557288 | 0.74 | DHFR (0.48) | DHFR | |
| SCHEMBL6555540 | 0.73 | DHFR (0.49) | DHFR | |
| SCHEMBL6555159 | 0.73 | DHFR (0.47) | DHFR | |
| SCHEMBL6555139 | 0.72 | DHFR (0.54) | DHFR | |
| SCHEMBL6557302 | 0.72 | DHFR (0.52) | DHFR | |
| SCHEMBL6555101 | 0.72 | DHFR (0.52) | DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230224-A1 | SUBSTITUTED 5-BENZYL-2,4-DIAMINOPYRIMIDINES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001032633-A1 | SUBSTITUTED 5-BENZYL-2,4-DIAMINOPYRIMIDINES | BASILEA PHARMACEUTICA AG (CH) | 2001-05-10 | — | — | WO | disclosed |