Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 3/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | PLK4 | O00444 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PAK4 | O96013 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | PRKCG | P05129 | 1/20 | 0.37 |
| ▸ | INSR | P06213 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573073 | 0.96 | KDM4E (0.39) | KDM4EPIM1ADRB2MAPK1ALDH1A1 | |
| SCHEMBL7715410 | 0.89 | L3MBTL1 (0.39) | KDM4EPIM1MAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7572253 | 0.84 | CYP3A4 (0.46) | KDM4EPIM1CDC7ROCK2MAP4K4 | |
| SCHEMBL7573743 | 0.84 | MAPT (0.41) | KDM4EMAPK1ALDH1A1SMN1; SMN2SQOR | |
| SCHEMBL7580611 | 0.84 | MAPT (0.44) | KDM4EPIM1ALDH1A1SMN1; SMN2SQOR | |
| SCHEMBL7575694 | 0.82 | CNR2 (0.39) | CD274ALDH1A1PTPN11MAPTHPGD | |
| SCHEMBL7575492 | 0.82 | RARB (0.55) | ALDH1A1PTPN11HPGD | |
| SCHEMBL7573733 | 0.82 | GRM2 (0.41) | KDM4ECD274MAPK1SQORCYP1A2 | |
| SCHEMBL7572329 | 0.81 | PIM1 (0.41) | KDM4EPIM1MAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7572249 | 0.79 | CYP1A2 (0.46) | KDM4EMAPK1ALDH1A1SMN1; SMN2SQOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002096913-A1 | SUBSTITUTED DI(HYDROXY/ALKOXY)SILICON PHTHALOCYANINES AND THEIR USES | GENTIAN AS (NO) | 2002-12-05 | — | — | WO | disclosed |
| EP-1238016-A1 | SUBSTITUTED PHTHALOCYANINES AND THEIR PRECURSORS | Gentian AS (NO) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001042368-A1 | SUBSTITUTED PHTHALOCYANINES AND THEIR PRECURSORS | GENTIAN AS (NO) | 2001-06-14 | — | — | WO | disclosed |