Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573073 | 0.87 | KDM4E (0.39) | KDM4ENPC1ALDH1A1RAB9AMAPT | |
| SCHEMBL7580611 | 0.85 | MAPT (0.44) | CYP3A4CYP2D6KDM4ENPC1ALDH1A1 | |
| SCHEMBL7573743 | 0.85 | MAPT (0.41) | KDM4ENPC1ALDH1A1RAB9AHSD17B10 | |
| SCHEMBL7575694 | 0.84 | CNR2 (0.39) | ALDH1A1MAPTHPGD | |
| Dimethylamine SCHEMBL7572333 | 0.84 | KDM4E (0.39) | KDM4EALDH1A1MAPTCDC7ROCK2 | |
| SCHEMBL7572329 | 0.82 | PIM1 (0.41) | KDM4ENPC1ALDH1A1RAB9AMAPT | |
| SCHEMBL7576174 | 0.82 | PDE3A (0.46) | KDM4EALDH1A1LMNAMAPTPDE3A | |
| SCHEMBL7572014 | 0.81 | CYP2D6 (0.53) | CYP3A4CYP2D6KDM4ENPC1ALDH1A1 | |
| SCHEMBL7575492 | 0.81 | RARB (0.55) | ALDH1A1TSHRHPGD | |
| SCHEMBL7715410 | 0.81 | L3MBTL1 (0.39) | KDM4EALDH1A1MAPTPIM1SQOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002096913-A1 | SUBSTITUTED DI(HYDROXY/ALKOXY)SILICON PHTHALOCYANINES AND THEIR USES | GENTIAN AS (NO) | 2002-12-05 | — | — | WO | disclosed |
| EP-1238016-A1 | SUBSTITUTED PHTHALOCYANINES AND THEIR PRECURSORS | Gentian AS (NO) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001042368-A1 | SUBSTITUTED PHTHALOCYANINES AND THEIR PRECURSORS | GENTIAN AS (NO) | 2001-06-14 | — | — | WO | disclosed |