Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 12/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.37 |
| ▸ | PNP | P00491 | 4/20 | 0.37 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.35 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL678588 | 0.83 | ADRB3 (0.56) | ADRB3ADRB1ADRB2PNP | |
| SCHEMBL7593268 | 0.81 | ADRB3 (0.46) | ADRB3MAPK3MAPK1ADRB1ADRB2 | |
| SCHEMBL7779180 | 0.70 | ADRB3 (0.72) | ADRB3ADRB1ADRB2 | |
| SCHEMBL14252613 | 0.68 | ADRB2 (0.43) | ADRB3IDO1TDO2MAPK3MAPK1 | |
| SCHEMBL14338095 | 0.68 | ADRB2 (0.43) | ADRB3IDO1TDO2MAPK3MAPK1 | |
| SCHEMBL7782074 | 0.67 | ADRB3 (0.71) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7572351 | 0.67 | ADRB3 (0.81) | ADRB3ADRB1ADRB2 | |
| SCHEMBL27351455 | 0.66 | ADRB2 (0.43) | ADRB3IDO1TDO2MAPK3MAPK1 | |
| SCHEMBL5536670 | 0.65 | ADRB3 (0.48) | ADRB3ADRB1ADRB2 | |
| SCHEMBL14350620 | 0.65 | IDO1 (0.44) | ADRB3IDO1TDO2MAPK1ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235801-A2 | SOLID PHARMACEUTICAL PREPARATION | Dainippon Pharmaceutical Co., Ltd. (JP) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001040182-A3 | SOLID PHARMACEUTICAL PREPARATION | DAINIPPON PHARMACEUTICAL CO (JP) | 2002-06-27 | — | — | WO | disclosed |
| WO-2001040182-A2 | SOLID PHARMACEUTICAL PREPARATION | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 2001-06-07 | — | — | WO | disclosed |