Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4180791 | 1.00 | KMT2A (0.47) | KMT2AMEN1ALDH1A1LMNATSHR | |
| SCHEMBL4188849 | 0.91 | CYP2D6 (0.41) | KMT2ALMNATSHRCYP3A4HTT | |
| SCHEMBL10154532 | 0.83 | ATM (0.37) | KMT2AMEN1TSHRATML3MBTL1 | |
| SCHEMBL1928940 | 0.83 | ATM (0.37) | KMT2AMEN1TSHRATML3MBTL1 | |
| SCHEMBL30879112 | 0.82 | KMT2A (0.46) | KMT2AMEN1ALDH1A1LMNATSHR | |
| SCHEMBL30879113 | 0.82 | KMT2A (0.46) | KMT2AMEN1ALDH1A1LMNATSHR | |
| SCHEMBL5971112 | 0.82 | KMT2A (0.46) | KMT2AMEN1ALDH1A1LMNATSHR | |
| SCHEMBL5970972 | 0.78 | KMT2A (0.42) | KMT2AMEN1ALDH1A1LMNATSHR | |
| SCHEMBL9340565 | 0.77 | KMT2A (0.41) | KMT2AMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL19931345 | 0.77 | KMT2A (0.41) | KMT2AMEN1ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020028938-A1 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | BLACK LAWRENCE A (US) | 2002-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020028938-A1 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | PTGS1, PTGIS, PTGS2 | KMT2A 4365/4885MEN1 4595/4885ALDH1A1 286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.