Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ADK | P55263 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572694 | 1.00 | MAPT (0.45) | MAPTPTGS2MGAMGAASI | |
| SCHEMBL7573148 | 0.93 | GRIN2D (0.44) | MAPTPTGS2MAOBCYP1A2CYP2C9 | |
| SCHEMBL7573146 | 0.93 | GRIN2D (0.44) | MAPTPTGS2MAOBCYP1A2CYP2C9 | |
| SCHEMBL7571219 | 0.87 | ACHE (0.47) | MAPTPTGS2GAAMAOBMAOA | |
| SCHEMBL7581527 | 0.86 | MEN1 (0.49) | MAPTPTGS2MAOBCYP1A2CYP2C9 | |
| SCHEMBL7579070 | 0.86 | MEN1 (0.49) | MAPTPTGS2MAOBCYP1A2CYP2C9 | |
| SCHEMBL7579065 | 0.86 | MEN1 (0.49) | MAPTPTGS2MAOBCYP1A2CYP2C9 | |
| SCHEMBL7581536 | 0.86 | MEN1 (0.49) | MAPTPTGS2MAOBCYP1A2CYP2C9 | |
| SCHEMBL7579646 | 0.85 | ALDH1A1 (0.42) | MAPTPTGS2MGAMGAASI | |
| SCHEMBL7575172 | 0.85 | ALDH1A1 (0.42) | MAPTGAANPC1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810199-B1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5756769-A | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0810199-A1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |