Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5187335 | 1.00 | TSHR (0.42) | TSHRS1PR1GAAMAPTPKM | |
| SCHEMBL5809269 | 0.82 | TSHR (0.52) | TSHRMAPTHTTATMNISCH | |
| SCHEMBL8531953 | 0.80 | TSHR (0.46) | TSHRMAPTATMNISCHLMNA | |
| SCHEMBL4388491 | 0.80 | TSHR (0.46) | TSHRHTTATMNISCH | |
| SCHEMBL13774495 | 0.76 | TSHR (0.42) | TSHRS1PR1GAAMAPTPKM | |
| SCHEMBL5055700 | 0.76 | CYP2C9 (0.39) | TSHRS1PR1GAAPKMSMN1; SMN2 | |
| SCHEMBL24404669 | 0.75 | TSHR (0.42) | TSHRS1PR1MAPTLMNAMEN1 | |
| SCHEMBL25446015 | 0.72 | MAPT (0.40) | TSHRS1PR1MAPTLMNASMN1; SMN2 | |
| SCHEMBL12018923 | 0.71 | TSHR (0.33) | TSHRS1PR1MAPTHTTTP53 | |
| SCHEMBL24934080 | 0.71 | TSHR (0.47) | TSHRATMNISCHLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235117-A1 | Imaging members | Xerox Corporation (US) | 2002-08-28 | — | — | EP | disclosed |
| US-6319645-B1 | USEFUL IN ELECTROPHOTOGRAPHIC IMAGING AND PRINTING | XEROX CORPORATION | 2001-11-20 | — | — | US | disclosed |