SCHEMBL5809269

SCHEMBL5809269

CCC(C)c1ccccc1N(c1ccccc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
ATM Q13315 1/20 0.39
LMNA P02545 1/20 0.36
NISCH Q9Y2I1 1/20 0.36
KDM4E B2RXH2 3/20 0.35
L3MBTL1 Q9Y468 2/20 0.34
ALDH1A1 P00352 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
GLA P06280 1/20 0.33
TRPA1 O75762 1/20 0.33
PPARA Q07869 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8531953 0.93 TSHR (0.46) TSHRATMLMNANISCHKDM4E
SCHEMBL4388491 0.86 TSHR (0.46) TSHRATMNISCHKDM4EL3MBTL1
SCHEMBL3123215 0.84 TSHR (0.47) TSHRATMLMNANISCHKDM4E
SCHEMBL5187335 0.82 TSHR (0.42) TSHRATMLMNANISCHMAPT
SCHEMBL7572744 0.82 TSHR (0.42) TSHRATMLMNANISCHMAPT
SCHEMBL21913733 0.82 GABRA1 (0.41) TSHRLMNAKDM4EL3MBTL1ALDH1A1
SCHEMBL18904097 0.81 TSHR (0.44) TSHRATMLMNANISCHKDM4E
SCHEMBL5223350 0.80 TSHR (0.55) TSHRATMLMNANISCHKDM4E
SCHEMBL9748491 0.77 ALDH1A1 (0.39) TSHRATMKDM4EL3MBTL1ALDH1A1
Hydrogen Peroxide SCHEMBL3675725 0.77 TSHR (0.74) TSHRATMLMNAKDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101133098-B Polymers and electronic devices containing dicarbazol-9-yl-substituted triarylamines SUMITOMO CO LTD 2013-01-09 CN disclosed
CN-101878241-A Amine-type polymeric compound, and light-emitting element comprising the same SUMITOMO CHEMICAL CO 2010-11-03 CN disclosed
CN-101851190-A The triarylamine of two carbazoles-9-base-replacement SUMITOMO CHEMICAL CO 2010-10-06 CN disclosed
CN-101133098-A Polymers and electronic devices containing dicarbazol-9-yl-substituted triarylamines SUMITOMO CHEMICAL CO (JP) 2008-02-27 CN disclosed
WO-2006096332-A2 BISCARBAZOL-9-YL-SUBSTITUTED TRIARYLAMINE-CONTAINING POLYMERS AND ELECTRONIC DEVICES SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2006-09-14 WO disclosed