SCHEMBL24404669

SCHEMBL24404669

Cc1ccc(N(c2ccc(C)c(C)c2)c2ccccc2C)cc1C

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.42
ACHE P22303 1/20 0.42
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
S1PR1 P21453 1/20 0.35
MAPT P10636 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
ALDH1A1 P00352 2/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
CYP1A2 P05177 1/20 0.32
LMNA P02545 2/20 0.32
NQO2 P16083 1/20 0.31
POLB P06746 1/20 0.31
CYP3A4 P08684 2/20 0.31
TRPM8 Q7Z2W7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25446015 0.93 MAPT (0.40) TSHRACHEMEN1KMT2AS1PR1
SCHEMBL7763510 0.84 S1PR1 (0.36) TSHRACHEMEN1KMT2AS1PR1
SCHEMBL4893894 0.82 ACHE (0.43) TSHRACHEMAPTNPSR1ALDH1A1
SCHEMBL20210151 0.82 MAPK13 (0.40) TSHRACHES1PR1MAPTNPSR1
SCHEMBL11330069 0.82 HSD17B1 (0.35) TSHRACHESIGMAR1LMNACYP3A4
SCHEMBL1702664 0.81 CYP3A4 (0.35) TSHRACHEMEN1KMT2AMAPT
SCHEMBL24454788 0.81 ALDH1A1 (0.39) TSHRACHEMAPTALDH1A1CYP1A2
SCHEMBL8943827 0.80 ALDH1A1 (0.44) TSHRACHEMEN1KMT2AMAPT
SCHEMBL16627119 0.80 CYP2A6 (0.43) MEN1KMT2ANPSR1ALDH1A1SIGMAR1
SCHEMBL8943789 0.80 ACHE (0.45) TSHRACHEMAPTALDH1A1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3575877-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KK (JP) 2022-05-11 EP disclosed