Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | AR | P10275 | 2/20 | 0.66 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.66 |
| ▸ | IL1RN | P18510 | 1/20 | 0.66 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.66 |
| ▸ | PPARG | P37231 | 1/20 | 0.61 |
| ▸ | PGR | P06401 | 2/20 | 0.61 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.61 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572845 | 0.93 | KMT2A (0.67) | NR1H3MEN1KMT2AALDH1A1PKM | |
| SCHEMBL14601685 | 0.91 | MEN1 (0.65) | NR1H3MEN1KMT2AALDH1A1AR | |
| SCHEMBL12010912 | 0.89 | NR1H3 (0.68) | NR1H3MEN1KMT2AALDH1A1AR | |
| SCHEMBL12010881 | 0.85 | MEN1 (0.68) | NR1H3MEN1KMT2AALDH1A1AR | |
| SCHEMBL810795 | 0.84 | KMT2A (0.91) | MEN1KMT2AALDH1A1PKMKEAP1 | |
| SCHEMBL7577535 | 0.84 | CA1 (0.65) | MEN1KMT2AALDH1A1PKMAR | |
| SCHEMBL2415124 | 0.83 | NR1H3 (1.00) | NR1H3MEN1KMT2AALDH1A1PKM | |
| SCHEMBL7571036 | 0.83 | CES1 (0.73) | MEN1KMT2AALDH1A1ARPGR | |
| SCHEMBL18031173 | 0.83 | UQCRB (0.71) | NR1H3MEN1KMT2AARERAP1 | |
| SCHEMBL4573249 | 0.83 | KMT2A (0.71) | MEN1KMT2AALDH1A1ARKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382191-A1 | NOVEL BENZENESULFONAMIDES AS CALCIUM CHANNEL BLOCKERS | Abbott Laboratories, Inc. (US) | 2011-11-02 | — | — | EP | claimed |
| CN-108822002-B | Method for synthesizing N-aryl sulfonamide under assistance of ultrasonic waves | 中南大学 | 2020-05-05 | — | — | CN | disclosed |
| CN-108822002-A | A kind of method of ultrasonic wave added synthesis N- aryl sulfonic acid amides | 中南大学 | 2018-11-16 | — | — | CN | disclosed |
| US-8175860-B2 | Method of inhibiting the growth of Helicobacter pylori | NATIONAL TSING HUA UNIVERSITY (TW) | 2012-05-08 | — | — | US | disclosed |
| EP-2382191-A1 | NOVEL BENZENESULFONAMIDES AS CALCIUM CHANNEL BLOCKERS | Abbott Laboratories, Inc. (US) | 2011-11-02 | — | — | EP | disclosed |
| US-20100305152-A1 | METHOD OF INHIBITING THE GROWTH OF HELICOBACTER PYLORI | NATIONAL TSING HUA UNIVERSITY (TW) | 2010-12-02 | — | — | US | disclosed |
| EP-1519932-A1 | BISARYLSULFONAMIDE COMPOUNDS AND THEIR USE IN CANCER THERAPY | Cyclacel Limited (GB) | 2005-04-06 | — | — | EP | disclosed |
| WO-2004005278-A1 | BISARYLSULFONAMIDE COMPOUNDS AND THEIR USE IN CANCER THERAPY | CYCLACEL LIMITED (GB) | 2004-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305152-A1 | METHOD OF INHIBITING THE GROWTH OF HELICOBACTER PYLORI | HPD, HAAO, HK1 | NR1H3 3143/4885MEN1 2935/4885KMT2A 2315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.