Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 1/20 | 0.33 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537138 | 0.73 | ALDH1A1 (0.37) | — | |
| SCHEMBL5174277 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL5475854 | 0.71 | ALDH1A1 (0.35) | — | |
| SCHEMBL10945547 | 0.71 | LOX (0.43) | LOXLOXL3LOXL2 | |
| SCHEMBL1997210 | 0.69 | LOX (0.32) | LOXLOXL3LOXL2 | |
| Bromide SCHEMBL5276683 | 0.69 | NFKB1 (0.32) | LOXLOXL3LOXL2 | |
| SCHEMBL11143017 | 0.69 | MEN1 (0.32) | — | |
| SCHEMBL18602278 | 0.69 | ALDH1A1 (0.33) | — | |
| SCHEMBL3797709 | 0.67 | — | — | |
| SCHEMBL2992485 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| EP-0934278-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017650-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1998-04-30 | — | — | WO | disclosed |