Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 1/20 | 0.32 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2992485 | 0.72 | — | — | |
| SCHEMBL10399668 | 0.72 | — | — | |
| SCHEMBL1863727 | 0.72 | — | — | |
| SCHEMBL17595579 | 0.72 | — | — | |
| SCHEMBL7572872 | 0.69 | LOX (0.33) | LOXLOXL3LOXL2 | |
| SCHEMBL5174277 | 0.67 | — | — | |
| SCHEMBL9537138 | 0.67 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL29834982 | 0.67 | — | — | |
| SCHEMBL13623250 | 0.67 | ALDH1A1 (0.36) | ALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL5475854 | 0.65 | ALDH1A1 (0.35) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1207149-B1 | Process for the hydrogenation of nitriles on Raney catalysts | BASF AG (DE) | 2005-01-26 | — | — | EP | claimed |
| EP-1209146-B1 | Process for the hydrogenation of nitriles to primary amines using Raney-catalysts | BASF AG (DE) | 2004-06-30 | — | — | EP | claimed |
| US-6677486-B2 | HYDROGENATING NITRITES TO PRIMARY AMINES OVER AN ACTIVATED, ALPHA-ALUMINUM OXIDE(AL2O3)-CONTAINING, MACROPOROUS RANEY CATALYST BASED ON AN ALLOY OF ALUMINUM AND AT LEAST ONE TRANSITION METAL | BASF AKTIENGESELLSCHAFT (DE) | 2004-01-13 | — | — | US | claimed |
| US-6469211-B2 | CONTINUOUS HYDROGENATION OF NITRITES TO PRIMARY AMINES IN THE LIQUID PHASE OVER A SUSPENDED, ACTIVATED RANEY CATALYST BASED ON AN ALLOY OF ALUMINUM AND AT LEAST ONE TRANSITION METAL, IN ABSENCE OF AMMONIA | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-22 | — | — | US | claimed |
| US-20020058841-A1 | Hydrogenation of nitriles over Raney catalysts | BASF AKTIENGESELLSCHAFT (DE) | 2002-05-16 | — | — | US | claimed |
| US-20020058842-A1 | Hydrogenation of nitriles over raney catalysts | BASF AKTIENGESELLSCHAFT (DE) | 2002-05-16 | — | — | US | claimed |
| EP-0382508-B1 | The preparation of polyamines | HAMPSHIRE CHEMICAL CORP (US) | 1994-11-30 | — | — | EP | claimed |
| EP-0212986-B1 | Synthesis of aliphatic polyamines | GRACE W R & CO (US) | 1994-01-19 | — | — | EP | claimed |
| US-5097072-A | Hydrogenation of polynitriles; raney cobalt-nickel catalyst | W.R. GRACE & CO.-CONN. (US) | 1992-03-17 | — | — | US | claimed |
| EP-0382508-A2 | The preparation of polyamines | HAMPSHIRE CHEMICAL CORPORATION (US) | 1990-08-16 | — | — | EP | claimed |
| US-4721811-A | Synthesis of aliphatic polyamines | W. R. GRACE & CO. (US) | 1988-01-26 | — | — | US | claimed |
| US-4704465-A | Process for preparing ethylenediaminetetraacetonitrile | MONSANTO COMPANY (US) | 1987-11-03 | — | — | US | claimed |
| EP-0212986-A1 | Synthesis of aliphatic polyamines | W.R. Grace & Co.-Conn. (US) | 1987-03-04 | — | — | EP | claimed |
| US-4181672-A | Process for preparing metal chelates | W. R. GRACE & CO. (US) | 1980-01-01 | — | — | US | claimed |
| US-3972876-A | Process for the preparation of symmetrical and unsymmetrical azines and mixtures thereof | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1976-08-03 | — | — | US | claimed |
| US-9869027-B2 | Cleaning composition and method of manufacturing metal wiring using the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-01-16 | — | — | US | disclosed |
| US-9340759-B2 | Cleaning composition and method of manufacturing metal wiring using the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2016-05-17 | — | — | US | disclosed |
| US-4478759-A | Preparation of aminoitriles | BASF AKTIENGESELLSCHAFT (DE) | 1984-10-23 | — | — | US | disclosed |
| US-4181672-A | Process for preparing metal chelates | W. R. GRACE & CO. (US) | 1980-01-01 | — | — | US | disclosed |
| US-4181672-A | Process for preparing metal chelates | W. R. GRACE & CO. (US) | 1980-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058841-A1 | Hydrogenation of nitriles over Raney catalysts | NUAK2, NUAK1, WNK3 | LOX 2320/4885LOXL3 3378/4885LOXL2 3500/4885 |
| US-20020058842-A1 | Hydrogenation of nitriles over raney catalysts | NOS2, NPM1, NOS3 | LOX 3242/4885LOXL3 4441/4885LOXL2 4544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.