Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5670577 | 0.79 | L3MBTL1 (0.58) | PARP1ALDH1A1HPGDGAATSHR | |
| SCHEMBL3249363 | 0.79 | PARP1 (0.62) | PARP1ALDH1A1HPGDGAATSHR | |
| SCHEMBL3641415 | 0.78 | PARP1 (0.56) | PARP1ALDH1A1HPGDGAATSHR | |
| SCHEMBL4821188 | 0.76 | PARP1 (0.58) | PARP1ALDH1A1HPGDGAATSHR | |
| SCHEMBL5670687 | 0.76 | ALDH1A1 (0.56) | PARP1ALDH1A1HPGDGAATSHR | |
| SCHEMBL5671330 | 0.76 | PARP1 (0.54) | PARP1ALDH1A1HPGDGAATSHR | |
| SCHEMBL5670842 | 0.75 | ALDH1A1 (0.65) | ALDH1A1HPGDGAATSHRUSP2 | |
| SCHEMBL5670690 | 0.74 | PARP1 (0.55) | PARP1ALDH1A1HPGDGAATSHR | |
| SCHEMBL22186873 | 0.74 | PARP1 (0.51) | PARP1ALDH1A1HPGDGAATSHR | |
| SCHEMBL5671346 | 0.74 | ALDH1A1 (0.54) | PARP1ALDH1A1HPGDGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206458-A1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND THE USE THEREOF IN MEDICAMENTS | Schering Aktiengesellschaft (DE) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001014347-A1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND THE USE THEREOF IN MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-03-01 | — | — | WO | disclosed |