SCHEMBL7572922

SCHEMBL7572922

Oc1ccc(O)c(CS)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 7/20 0.50
TYR P14679 3/20 0.46
LCK P06239 2/20 0.42
ALDH1A1 P00352 4/20 0.40
MAPT P10636 4/20 0.40
RGS12 O14924 1/20 0.40
CAMKK2 Q96RR4 1/20 0.40
NOX4 Q9NPH5 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
LMNA P02545 4/20 0.39
HTT P42858 4/20 0.39
CYP3A4 P08684 3/20 0.39
ALOX15 P16050 3/20 0.39
GAA P10253 2/20 0.39
CYP2C9 P11712 2/20 0.39
HPGD P15428 2/20 0.39
ALOX12 P18054 2/20 0.39
HIF1A Q16665 2/20 0.39
HSD17B10 Q99714 2/20 0.39
MEN1 O00255 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20271248 0.82 TYR (0.48) EGFRTYRALDH1A1MAPTTDP1
SCHEMBL10912123 0.80 TYR (0.65) TYRMAPTTDP1HTTCYP3A4
SCHEMBL31244463 0.79 MAPT (0.58) EGFRTYRLCKALDH1A1MAPT
SCHEMBL50932 0.79 MAPT (0.58) EGFRTYRLCKALDH1A1MAPT
SCHEMBL10012940 0.79 TYR (0.64) EGFRTYRLCKALDH1A1CYP3A4
SCHEMBL16982325 0.78 GABRA1 (0.45) ALDH1A1MAPTTDP1LMNAHTT
Gentisyl Alcohol SCHEMBL829492 0.77 KLF10 (0.54) EGFRTYRLCKALDH1A1MAPT
SCHEMBL23841643 0.76 HSD17B10 (0.52) TYRMAPTHSD17B10MEN1KMT2A
SCHEMBL10321611 0.76 HPGD (0.68) ALDH1A1MAPTTDP1LMNAHTT
SCHEMBL14599886 0.76 AMY1A (0.59) ALDH1A1MAPTTDP1LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108431149-B Anti-biofouling coatings based on epoxy resins and amine functional polysiloxanes 陶氏环球技术有限责任公司 2020-11-20 CN disclosed
WO-2008020034-A1 USE OF 2,5-DIHYDROXYBENZENE DERIVATIVES FOR THE TREATMENT OF HEMANGIOMAS OR HEMANGIOBLASTOMAS ACTION MEDICINES, S.L. (ES) 2008-02-21 WO disclosed
WO-2008020037-A1 USE OF 2,5-DIHYDROXYBENZENE DERIVATIVES FOR TREATING OBESITY, HIRSUTISM, HYPERTRICOSIS AND VIRAL WARTS ACTION MEDICINES, S.L. (ES) 2008-02-21 WO disclosed
WO-2008020031-A1 USE OF 2,5-DIHYDROXYBENZENE DERIVATIVES FOR THE TREATMENT OF ANGIOGENIC DISEASES ACTION MEDICINES, S.L. (ES) 2008-02-21 WO disclosed
WO-2008020033-A1 USE OF 2,5-DIHYDROXYBENZENE DERIVATIVES FOR THE TREATMENT OF ARTHRITIS AND PAIN ACTION MEDICINES, S.L. (ES) 2008-02-21 WO disclosed
WO-2008020025-A1 USE OF 2,5-DIHYDROXYBENZENE DERIVATIVES FOR TREATING ACTINIC KERATOSIS ACTION MEDICINES, S.L. (ES) 2008-02-21 WO disclosed
WO-2008020032-A1 USE OF 2,5-DIHYDROXYBENZENE DERIVATIVES FOR THE TREATMENT OF OCULAR DISEASES ACTION MEDICINES, S.L. (ES) 2008-02-21 WO disclosed
WO-2008020042-A1 USE OF 2, 5-DIHYDROXYBENZENE DERIVATIVES FOR THE TREATMENT OF TISSUE REACTIVE DISEASES ACTION MEDICINES, S.L. (ES) 2008-02-21 WO disclosed
EP-0669949-B1 TERTIARY AMINE DERIVATIVES AS COMPONENTS OF POLYMER FORMING SYSTEMS COGNIS CORP (US) 2002-03-13 EP disclosed
EP-0669949-A4 TERTIARY AMINE DERIVATIVES AS COMPONENTS OF POLYMER FORMING SYSTEMS. HENKEL CORP (US) 1996-07-10 EP disclosed
EP-0669949-A1 TERTIARY AMINE DERIVATIVES AS COMPONENTS OF POLYMER FORMING SYSTEMS HENKEL CORPORATION (US) 1995-09-06 EP disclosed
US-5444127-A Urea, thiourea, guanidine derivatives, curing agents for epoxy resins, odorless, low temperature HENKEL CORPORATION (US) 1995-08-22 US disclosed
WO-1994009051-A1 TERTIARY AMINE DERIVATIVES AS COMPONENTS OF POLYMER FORMING SYSTEMS HENKEL CORPORATION (US) 1994-04-28 WO disclosed
EP-0014745-B1 CURING AGENT FOR POLYEPOXIDES, CURABLE EPOXY RESIN COMPOSITIONS, HARDENED PRODUCTS THEREFROM AND PROCESS FOR CURING A POLYEPOXIDE DIAMOND SHAMROCK CORPORATION (US) 1983-05-25 EP disclosed
EP-0075827-A2 Polyepoxide curing by polymercaptans plus catalytic co-curing agents DIAMOND SHAMROCK CHEMICALS COMPANY (US) 1983-04-06 EP disclosed
EP-0014745-A1 Curing agent for polyepoxides, curable epoxy resin compositions, hardened products therefrom and process for curing a polyepoxide DIAMOND SHAMROCK CORPORATION (US) 1980-09-03 EP disclosed
US-4177173-A INFUSIBLE FILMS, CASTINGS OR ADHESIVES DIAMOND SHAMROCK CORPORATION (US) 1979-12-04 US disclosed