Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20419769 | 0.88 | PTGS2 (0.62) | PTGS2MAPTALOX15KDM4EGLA | |
| SCHEMBL7573522 | 0.80 | PTGS2 (0.53) | PTGS2MAPTALOX15KDM4EGLA | |
| SCHEMBL7025322 | 0.78 | MAPT (0.61) | PTGS2MAPTALOX15KDM4EGLA | |
| SCHEMBL20419774 | 0.74 | RAPGEF4 (0.54) | PTGS2 | |
| SCHEMBL16656521 | 0.74 | PTGS2 (0.66) | PTGS2MAPTALOX15KDM4EGLA | |
| SCHEMBL6808925 | 0.74 | PTGS2 (0.62) | PTGS2MAPTALOX15KDM4EGLA | |
| SCHEMBL19065779 | 0.73 | MAPT (0.79) | PTGS2MAPTALOX15KDM4EGLA | |
| SCHEMBL20419768 | 0.73 | FTO (0.65) | PTGS2MAPTKMT2AHSD17B10METTL3 | |
| SCHEMBL17145917 | 0.73 | MAPT (0.67) | PTGS2MAPTALOX15KDM4EGLA | |
| SCHEMBL30294456 | 0.73 | MAPT (0.67) | PTGS2MAPTALOX15KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |