SCHEMBL7572990

SCHEMBL7572990

CN(Cc1ccccc1)CC1CO1.CNCC1CO1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
LMNA P02545 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
BLM P54132 1/20 0.41
CARM1 Q86X55 1/20 0.39
PRMT6 Q96LA8 1/20 0.39
PRMT8 Q9NR22 1/20 0.39
KDM4E B2RXH2 3/20 0.39
NPC1 O15118 1/20 0.39
GAA P10253 1/20 0.39
RAB9A P51151 1/20 0.39
TSHR P16473 2/20 0.38
CYP3A4 P08684 2/20 0.38
USP2 O75604 1/20 0.38
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
PYCR1 P32322 1/20 0.38
SLC6A4 P31645 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4326995 0.89 ALDH1A1 (0.49) ALDH1A1LMNASMN1; SMN2BLMCARM1
SCHEMBL4334028 0.89 ALDH1A1 (0.49) ALDH1A1LMNASMN1; SMN2BLMCARM1
SCHEMBL3665986 0.89 ALDH1A1 (0.49) ALDH1A1LMNASMN1; SMN2BLMCARM1
Diphenylmethane SCHEMBL6887153 0.81 CHRM2 (0.47) KDM4ECYP3A4MEN1KMT2AMAPT
SCHEMBL5417196 0.78 ALDH1A1 (0.39) ALDH1A1LMNASMN1; SMN2BLMKDM4E
SCHEMBL12215364 0.74 PYCR1 (0.50) ALDH1A1SMN1; SMN2KDM4EMAOBPYCR1
SCHEMBL5474230 0.73 CARM1 (0.53) ALDH1A1LMNASMN1; SMN2BLMCARM1
SCHEMBL5482881 0.73 CARM1 (0.53) ALDH1A1LMNASMN1; SMN2BLMCARM1
SCHEMBL5474228 0.73 CARM1 (0.53) ALDH1A1LMNASMN1; SMN2BLMCARM1
SCHEMBL1190859 0.73 OXTR (0.51) ALDH1A1GAAMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1222232-A1 THERMOFORMABLE POLYAMIDES Bayer Aktiengesellschaft (DE) 2002-07-17 EP disclosed
WO-2001027202-A1 THERMOFORMABLE POLYAMIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-04-19 WO disclosed