Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | CHAT | P28329 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21803707 | 0.98 | BLM (0.48) | MEN1KMT2AMAPTMITFHTT | |
| SCHEMBL2776015 | 0.80 | CHAT (0.60) | MEN1KMT2AMAPTMITFHTT | |
| SCHEMBL29661843 | 0.80 | CHAT (0.60) | MEN1KMT2AMAPTMITFHTT | |
| SCHEMBL6447254 | 0.80 | CYP2C19 (0.61) | MAPTCYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1858300 | 0.80 | MEN1 (0.48) | MEN1KMT2AMAPTMITFHTT | |
| SCHEMBL730382 | 0.80 | MEN1 (0.48) | MEN1KMT2AMAPTMITFHTT | |
| SCHEMBL27481040 | 0.80 | CHAT (0.49) | MEN1KMT2AMAPTMITFHTT | |
| SCHEMBL6364668 | 0.78 | CHAT (0.58) | MEN1KMT2AMAPTMITFHTT | |
| SCHEMBL21592257 | 0.78 | CYP2A6 (0.49) | HTTCYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1612398 | 0.77 | TLR8 (0.50) | MEN1KMT2AMAPTMITFHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810199-B1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5756769-A | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0810199-A1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |