Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | LTK | P29376 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27693511 | 0.84 | ESR2 (0.48) | ALDH1A1HSD17B10MAPTUSP30ESR2 | |
| SCHEMBL57735 | 0.81 | ALDH1A1 (0.42) | ALDH1A1HSD17B10BCAT2DPP4ESR2 | |
| SCHEMBL1822460 | 0.78 | ALDH1A1 (0.62) | ALDH1A1HSD17B10MAPTBCAT2LIMK1 | |
| SCHEMBL1644568 | 0.78 | ALDH1A1 (0.39) | ALDH1A1HSD17B10BCAT2LIMK1CLK4 | |
| SCHEMBL4508095 | 0.78 | HDAC4 (0.45) | ALDH1A1HSD17B10MAPTBCAT2LIMK1 | |
| SCHEMBL11390415 | 0.77 | ALDH1A1 (0.50) | ALDH1A1HSD17B10ESR2HPGDMAPK1 | |
| SCHEMBL11390626 | 0.76 | PDCD1 (0.48) | ALDH1A1HSD17B10HNF4AHPGDMAPK1 | |
| SCHEMBL11393405 | 0.76 | CYP2A6 (0.45) | ALDH1A1HSD17B10BCAT2LIMK1CLK4 | |
| SCHEMBL7764189 | 0.76 | HDAC4 (0.53) | ALDH1A1HSD17B10BCAT2ESR2HNF4A | |
| Hydrochloric Acid SCHEMBL27842035 | 0.75 | ALDH1A1 (0.59) | ALDH1A1HSD17B10MAPTBCAT2LIMK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002079753-A2 | 2-AMINOBENZOXAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2002-10-10 | — | — | WO | claimed |