Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL224641 | 0.93 | CASP3 (0.42) | ALDH1A1HSD17B10HPGDBCL2L1CYP2A6 | |
| SCHEMBL6281274 | 0.84 | MEN1 (0.40) | ALDH1A1MAPK1ESR2TDP1BACE1 | |
| SCHEMBL8491741 | 0.83 | FFAR1 (0.49) | ALDH1A1HSD17B10HPGDESR2FFAR1 | |
| SCHEMBL4508095 | 0.82 | HDAC4 (0.45) | ALDH1A1HSD17B10HPGDBCL2L1CYP2A6 | |
| SCHEMBL1644568 | 0.82 | ALDH1A1 (0.39) | ALDH1A1HSD17B10HPGDBCL2L1CYP2A6 | |
| SCHEMBL1826260 | 0.82 | ESR2 (0.41) | ALDH1A1HPGDMAPK1ESR2TDP1 | |
| SCHEMBL2795998 | 0.82 | PTGS2 (0.47) | ALDH1A1ESR2CASP3SENP8SENP7 | |
| SCHEMBL7996184 | 0.81 | ESR2 (0.39) | ALDH1A1HSD17B10HPGDBCL2L1CYP2A6 | |
| SCHEMBL7764189 | 0.81 | HDAC4 (0.53) | ALDH1A1HSD17B10HPGDBCL2L1ESR2 | |
| SCHEMBL11393405 | 0.81 | CYP2A6 (0.45) | ALDH1A1HSD17B10HPGDBCL2L1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1496 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290333-A | Novel inhibitors of gonorrhoeae-specific tyrosine phosphatase (LYP) | 普渡研究基金会 | 2024-07-05 | — | — | CN | claimed |
| CN-115461056-B | Inhibitors of Lebaba-specific tyrosine phosphatase (LYP) | 普渡研究基金会 | 2024-04-16 | — | — | CN | claimed |
| US-11629130-B2 | Lymphoid-specific tyrosine phosphatase (LYP) inhibitors | PURDUE RESEARCH FOUNDATION (US) | 2023-04-18 | — | — | US | claimed |
| EP-4135711-A1 | NOVEL LYMPHOID-SPECIFIC TYROSINE PHOSPHATASE (LYP) INHIBITORS | Purdue Research Foundation (US) | 2023-02-22 | — | — | EP | claimed |
| CN-115505100-A | Epoxy resin based on spirosilafluorene as skeleton and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-12-23 | — | — | CN | claimed |
| CN-115505099-A | Epoxy resin containing carbazole structure and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-12-23 | — | — | CN | claimed |
| CN-115461056-A | Novel lymphoid specific tyrosine phosphatase (LYP) inhibitors | 普渡研究基金会 | 2022-12-09 | — | — | CN | claimed |
| CN-114895535-B | Super-resolution lithography method based on double-step absorption effect and STED principle | 之江实验室 | 2022-12-02 | — | — | CN | claimed |
| US-20210323926-A1 | Novel Lymphoid-Specific Tyrosine Phosphatase (LYP) Inhibitors | PURDUE RESEARCH FOUNDATION (US) | 2021-10-21 | — | — | US | claimed |
| WO-2021211191-A1 | NOVEL LYMPHOID-SPECIFIC TYROSINE PHOSPHATASE (LYP) INHIBITORS | PURDUE RESEARCH FOUNDATION (US) | 2021-10-21 | — | — | WO | claimed |
| EP-0411332-A1 | Antiviral peptides having a 2-oxoalkyl amino acid side chain | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1991-02-06 | — | — | EP | claimed |
| EP-0408973-A1 | Antiherpes pentapeptides | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1991-01-23 | — | — | EP | claimed |
| US-4942087-A | LIQUID CRYSTALS, POLYESTERS, POLYLACTAMS COPOLYMERS | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1990-07-17 | — | — | US | claimed |
| US-4923886-A | VASODILATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-05-08 | — | — | US | claimed |
| EP-0323160-A2 | Films of wholly aromatic polyester and processes for preparation thereof | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1989-07-05 | — | — | EP | claimed |
| US-4808575-A | BACTERICIDES, ANTIBIOTIC | SCHERING CORPORATION (US) | 1989-02-28 | — | — | US | claimed |
| US-4269773-A | CEPHALOSPORINS | SHIONOGI & CO., LTD. (JP) | 1981-05-26 | — | — | US | claimed |
| US-4260609-A | Di- and tri- substituted thiazoles | MERCK & CO., INC. (US) | 1981-04-07 | — | — | US | claimed |
| US-4259341-A | Di- and tri-substituted thiazoles | MERCK & CO., INC. (US) | 1981-03-31 | — | — | US | claimed |
| US-4233301-A | ADRENERGIC BLOCKING AGENTS | MERCK & CO., INC. (US) | 1980-11-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11629130-B2 | Lymphoid-specific tyrosine phosphatase (LYP) inhibitors | PTPN22, PTPN1, PTPRCAP | ALDH1A1 2774/4885HSD17B10 1823/4885HPGD 4245/4885 |
| US-20210323926-A1 | Novel Lymphoid-Specific Tyrosine Phosphatase (LYP) Inhibitors | PTPN22, PTPN1, PTPRCAP | ALDH1A1 2786/4885HSD17B10 1662/4885HPGD 4158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.