Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.71 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.71 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.69 |
| ▸ | CRHBP | P24387 | 1/20 | 0.69 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.69 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.63 |
| ▸ | EP300 | Q09472 | 1/20 | 0.61 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.61 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2068293 | 0.92 | HKDC1 (0.70) | KEAP1NFE2L2HSP90AA1CRHBPCRHR2 | |
| SCHEMBL30238204 | 0.92 | KEAP1 (0.61) | KEAP1NFE2L2HSP90AA1CRHBPCRHR2 | |
| SCHEMBL6295723 | 0.85 | CHEK1 (0.75) | KEAP1NFE2L2HSP90AA1CRHBPCRHR2 | |
| SCHEMBL7573136 | 0.84 | KEAP1 (0.76) | KEAP1NFE2L2HSP90AA1CRHBPCRHR2 | |
| SCHEMBL18870843 | 0.84 | HKDC1 (0.67) | KEAP1NFE2L2HSP90AA1CRHBPCRHR2 | |
| SCHEMBL31238776 | 0.84 | HSP90AA1 (0.55) | KEAP1NFE2L2HSP90AA1CRHBPCRHR2 | |
| SCHEMBL30620530 | 0.84 | ALDH1A1 (0.65) | KEAP1NFE2L2HSP90AA1CRHBPCRHR2 | |
| SCHEMBL3984291 | 0.82 | METAP2 (0.82) | KEAP1NFE2L2HSP90AA1CRHBPCRHR2 | |
| SCHEMBL9178476 | 0.80 | LMNA (0.73) | KEAP1NFE2L2EP300KAT2BKAT8 | |
| SCHEMBL7571483 | 0.79 | LMNA (0.67) | KEAP1NFE2L2HSP90AA1CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7902207-B2 | Process for production of amines | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-03-08 | — | — | US | disclosed |
| US-20070142639-A1 | Process for production of amines | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142639-A1 | Process for production of amines | SMS, CCNT1, PEAK1 | KEAP1 1733/4885NFE2L2 1195/4885HSP90AA1 3361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.