Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 2/20 | 0.36 |
| ▸ | PGK2 | P07205 | 2/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 5/20 | 0.33 |
| ▸ | F2 | P00734 | 3/20 | 0.33 |
| ▸ | PHGDH | O43175 | 4/20 | 0.33 |
| ▸ | PTPRB | P23467 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
| ▸ | KLK1 | P06870 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6804622 | 0.89 | THRA (0.33) | SLC9A1F10F2PHGDHLMNA | |
| SCHEMBL6797073 | 0.87 | PHGDH (0.43) | PHGDH | |
| SCHEMBL6798620 | 0.84 | ACP3 (0.32) | PGK1PGK2 | |
| Bromide SCHEMBL6797834 | 0.84 | ACP3 (0.31) | PGK1PGK2 | |
| SCHEMBL6798602 | 0.81 | THRA (0.36) | SLC9A1F10F2PHGDHLMNA | |
| SCHEMBL6798150 | 0.81 | PHGDH (0.33) | SLC9A1F10F2PHGDHITGB3 | |
| SCHEMBL6799000 | 0.77 | PGK1 (0.36) | PGK1PGK2SLC9A1F10F2 | |
| SCHEMBL6795651 | 0.75 | HPGD (0.41) | PTPRBALDH1A1 | |
| SCHEMBL6795254 | 0.74 | LDHA (0.30) | — | |
| SCHEMBL6794680 | 0.74 | PHGDH (0.34) | SLC9A1PHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1238971-A1 | SUBSTITUTED GUANIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2002-09-11 | — | — | EP | disclosed |