Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 11/20 | 0.46 |
| ▸ | MMP13 | P45452 | 11/20 | 0.46 |
| ▸ | MMP9 | P14780 | 10/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 9/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573430 | 1.00 | MMP1 (0.46) | MMP1MMP13MMP9ADAM17MEN1 | |
| SCHEMBL7504012 | 0.93 | MMP1 (0.45) | MMP1MMP13MMP9ADAM17MEN1 | |
| SCHEMBL7453313 | 0.92 | MMP1 (0.57) | MMP1MMP13MMP9ADAM17MMP12 | |
| SCHEMBL7509306 | 0.82 | MMP9 (0.54) | MMP1MMP13MMP9ADAM17CYP2C9 | |
| SCHEMBL7319849 | 0.82 | MMP9 (0.54) | MMP1MMP13MMP9ADAM17CYP2C9 | |
| SCHEMBL7553160 | 0.80 | MMP13 (0.55) | MMP1MMP13MMP9ADAM17CYP2C9 | |
| SCHEMBL7322413 | 0.80 | MMP13 (0.55) | MMP1MMP13MMP9ADAM17CYP2C9 | |
| SCHEMBL7453309 | 0.79 | MEN1 (0.44) | MMP1MMP13MMP9ADAM17MEN1 | |
| SCHEMBL7317053 | 0.78 | MMP9 (0.46) | MMP1MMP13MMP9ADAM17CYP2C9 | |
| SCHEMBL7321309 | 0.76 | MMP9 (0.51) | MMP1MMP13MMP9ADAM17MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0938471-B1 | THE PREPARATION AND USE OF ORTHO-SULFONAMIDO ARYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASE AND TACE INHIBITORS | AMERICAN CYANAMID CO (US) | 2001-12-12 | — | — | EP | disclosed |
| EP-0938471-A1 | THE PREPARATION AND USE OF ORTHO-SULFONAMIDO ARYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASE AND TACE INHIBITORS | American Cyanamid Company (US) | 1999-09-01 | — | — | EP | disclosed |
| WO-1998016503-A2 | THE PREPARATION AND USE OF ORTHO-SULFONAMIDO ARYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASE AND TACE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1998-04-23 | — | — | WO | disclosed |