Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 3/20 | 0.77 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
| ▸ | TTR | P02766 | 3/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.49 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.49 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.49 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7759632 | 0.87 | CLCN2 (1.00) | CLCN2PTGS2MAPTAKR1B10ABCB11 | |
| SCHEMBL27516871 | 0.86 | CLCN2 (0.76) | CLCN2PTGS2MAPTKDM4EALDH1A1 | |
| SCHEMBL22169241 | 0.83 | CLCN2 (0.71) | CLCN2PTGS2MAPTKDM4EALDH1A1 | |
| SCHEMBL10699208 | 0.80 | CLCN2 (0.66) | CLCN2PTGS2MAPTKDM4EALDH1A1 | |
| SCHEMBL28277819 | 0.79 | PTGS2 (0.59) | CLCN2PTGS2KDM4EALDH1A1AKR1B10 | |
| Acetic Acid SCHEMBL3807274 | 0.78 | PTGS2 (0.70) | CLCN2PTGS2GAAAKR1B10ABCB11 | |
| SCHEMBL27661779 | 0.77 | CLCN2 (0.63) | CLCN2PTGS2MAPTKDM4EALDH1A1 | |
| SCHEMBL23643039 | 0.77 | KMT2A (0.60) | CLCN2MAPTALDH1A1GAAKMT2A | |
| SCHEMBL7164856 | 0.77 | PTGS2 (0.83) | CLCN2PTGS2GAAAKR1B10ABCB11 | |
| SCHEMBL20419707 | 0.76 | CLCN2 (0.75) | CLCN2PTGS2MAPTAKR1B10ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |