Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 6/20 | 1.00 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.55 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.55 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.55 |
| ▸ | DHFR | P00374 | 1/20 | 0.55 |
| ▸ | MPO | P05164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573477 | 0.87 | CLCN2 (0.77) | CLCN2FTOPTGS2MEN1AKR1C3 | |
| SCHEMBL27516871 | 0.86 | CLCN2 (0.76) | CLCN2PTGS2MEN1AKR1C3KMT2A | |
| SCHEMBL20419707 | 0.86 | CLCN2 (0.75) | CLCN2FTOPTGS2MEN1AKR1C3 | |
| SCHEMBL22169241 | 0.83 | CLCN2 (0.71) | CLCN2FTOPTGS2MEN1AKR1C3 | |
| SCHEMBL7164856 | 0.80 | PTGS2 (0.83) | CLCN2PTGS2AKR1C3KMT2ALMNA | |
| SCHEMBL10699208 | 0.80 | CLCN2 (0.66) | CLCN2PTGS2MEN1KMT2AAKR1B10 | |
| SCHEMBL7851667 | 0.79 | PTGS2 (0.73) | CLCN2FTOPTGS2MEN1AKR1C3 | |
| SCHEMBL24021567 | 0.79 | CLCN2 (1.00) | CLCN2FTOPTGS2MEN1AKR1C3 | |
| SCHEMBL8555568 | 0.78 | PTGS2 (0.71) | CLCN2FTOPTGS2MEN1AKR1C3 | |
| SCHEMBL355549 | 0.78 | FABP4 (0.80) | CLCN2PTGS2MEN1AKR1C3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11173137-B2 | Compositions and methods to modulate chloride ion channel activity | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2021-11-16 | — | — | US | disclosed |
| US-20010044511-A1 | Polymerization of olefins | E.I. DU PONT DE NEMOURS AND COMPANY | 2001-11-22 | — | — | US | disclosed |
| WO-2001072854-A2 | POLYMERIZATION OF OLEFINS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2001-10-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11173137-B2 | Compositions and methods to modulate chloride ion channel activity | CLCN2, CLIC1, CLIC4 | CLCN2 1/4885FTO 4582/4885PTGS2 2251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.