Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 1/20 | 0.66 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.50 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.46 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.46 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.46 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6280428 | 0.88 | PTGS2 (0.74) | CLCN2PTGS2ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL1548694 | 0.86 | ALDH1A1 (0.54) | CLCN2PTGS2ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL16480270 | 0.86 | PTGS2 (0.68) | CLCN2PTGS2ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL764380 | 0.84 | PTGS2 (0.66) | CLCN2PTGS2KMT2AAKR1B10UGT1A9 | |
| SCHEMBL7164856 | 0.84 | PTGS2 (0.83) | CLCN2PTGS2KMT2AAKR1B10UGT1A9 | |
| SCHEMBL28429126 | 0.84 | SCN5A (0.59) | CLCN2PTGS2KCNH2SCN5ACACNA1C | |
| SCHEMBL14320839 | 0.80 | HTT (0.50) | CLCN2PTGS2ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7573477 | 0.80 | CLCN2 (0.77) | CLCN2PTGS2ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7759632 | 0.80 | CLCN2 (1.00) | CLCN2PTGS2MEN1KMT2AAKR1B10 | |
| SCHEMBL18734561 | 0.79 | RAPGEF4 (0.56) | CLCN2PTGS2ALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260651-A2 | Process for the preparation of a composition of parabutylated and octylated, ortho-ethylated diphenylamines | The B.F. GOODRICH Company (US) | 1988-03-23 | — | — | EP | disclosed |
| US-4704219-A | Novel composition of para-butylated and octylated, ortho-ethylated diphenylamines | THE B. F. GOODRICH COMPANY | 1987-11-03 | — | — | US | disclosed |