Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 1/20 | 0.53 |
| ▸ | CXCL8 | P10145 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1186465 | 0.87 | FABP4 (0.59) | CLCN2KMT2ALMNAMEN1PTGS2 | |
| Benzene SCHEMBL28132022 | 0.78 | ALDH1A1 (0.59) | KMT2ALMNAMEN1AKR1C3PTGS1 | |
| SCHEMBL29657201 | 0.78 | ALDH1A1 (0.59) | KMT2ALMNAMEN1AKR1C3PTGS1 | |
| SCHEMBL254364 | 0.78 | ALDH1A1 (0.59) | KMT2ALMNAMEN1AKR1C3PTGS1 | |
| Hydrogen Peroxide SCHEMBL9514730 | 0.78 | ALDH1A1 (0.59) | KMT2ALMNAMEN1AKR1C3PTGS1 | |
| Ammonia Solution, Strong SCHEMBL11877644 | 0.77 | ALDH1A1 (0.56) | KMT2ALMNAMEN1AKR1C3PTGS1 | |
| SCHEMBL28432760 | 0.77 | ALDH1A1 (0.56) | KMT2ALMNAMEN1AKR1C3PTGS1 | |
| SCHEMBL7573477 | 0.75 | CLCN2 (0.77) | CLCN2CXCL8KMT2ALMNAMEN1 | |
| Hydrazine SCHEMBL27571459 | 0.75 | ALDH1A1 (0.54) | KMT2ALMNAMEN1AKR1C3NAPRT | |
| Water SCHEMBL27489910 | 0.75 | ALDH1A1 (0.54) | KMT2ALMNAMEN1AKR1C3NAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |
| EP-0934278-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017650-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1998-04-30 | — | — | WO | disclosed |