Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | KLK1 | P06870 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.36 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.36 |
| ▸ | HPN | P05981 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24901520 | 0.79 | KDM4E (0.42) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL11418321 | 0.77 | KDM4E (0.38) | ALDH1A1KDM4EGAAGLAHPGD | |
| Hydrochloric Acid SCHEMBL23466978 | 0.77 | KDM4E (0.41) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL28479087 | 0.76 | ALOX15 (0.52) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL27787089 | 0.76 | GAA (0.65) | ALDH1A1KDM4EGAACYP1A2L3MBTL1 | |
| SCHEMBL28884407 | 0.76 | KDM6B (0.43) | — | |
| SCHEMBL15688828 | 0.74 | GAA (0.50) | ALDH1A1GAACYP1A2ALOX15MGAM | |
| SCHEMBL13044973 | 0.74 | ALDH1A1 (0.38) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL7285870 | 0.74 | PHF8 (0.52) | ALDH1A1KDM4ECYP1A2L3MBTL1ADRA1A | |
| SCHEMBL6116108 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582625-B2 | Selected CGRP antagonists, processes for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-09-01 | — | — | US | disclosed |
| EP-0637229-B1 | DEVICES FOR PREVENTING TISSUE ADHESION | OSTEOTECH INC (US) | 2002-11-20 | — | — | EP | disclosed |
| US-20020095213-A1 | PROSTHETIC DEVICES FORMED FROM MATERIALS HAVING BONE-BONDING PROPERTIES AND USES THEREFOR | ISOTIS N.V. (NL) | 2002-07-18 | — | — | US | disclosed |
| US-20010051832-A1 | PROSTHETIC DEVICES FORMED FROM MATERIALS HAVING BONE-BONDING PROPERTIES AND USES THEREFOR | ISOTIS N.V. (NL) | 2001-12-13 | — | — | US | disclosed |
| EP-0637229-A4 | DEVICES FOR PREVENTING TISSUE ADHESION. | OSTEOTECH INC (US) | 1998-11-25 | — | — | EP | disclosed |
| US-5508036-A | Devices for preventing tissue adhesion | OSTEOTECH, INC. (US) | 1996-04-16 | — | — | US | disclosed |
| US-5480436-A | MULTILAYER BIODEGRADABLE POLYMER SUCH AS BUTYLENE ETHYLENE TEREPHTHALATE COPOLYMER COMPOSITE LAYERS WITH PORES | OSTEOTECH, INC. (US) | 1996-01-02 | — | — | US | disclosed |
| EP-0637229-A1 | DEVICES FOR PREVENTING TISSUE ADHESION | OSTEOTECH, INC., (US) | 1995-02-08 | — | — | EP | disclosed |
| WO-1993021858-A9 | DEVICES FOR PREVENTING TISSUE ADHESION | — | 1994-02-03 | — | — | WO | disclosed |
| WO-1993021858-A1 | DEVICES FOR PREVENTING TISSUE ADHESION | OSTEOTECH, INC. (US) | 1993-11-11 | — | — | WO | disclosed |
| EP-0364016-A1 | Polyphosphazene polymers and their preparation | Stichting Biomaterials Science Center, VU, "BSC-VU" (NL) | 1990-04-18 | — | — | EP | disclosed |