SCHEMBL24901520

SCHEMBL24901520

CCC(=O)OCC(=O)N(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.42
NAAA Q02083 1/20 0.40
ALDH1A1 P00352 7/20 0.39
GAA P10253 2/20 0.39
MGAM O43451 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
SOAT1 P35610 1/20 0.39
CYP1A2 P05177 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CHRM2 P08172 1/20 0.37
CHRM4 P08173 1/20 0.37
CHRM5 P08912 1/20 0.37
CHRM1 P11229 1/20 0.37
CHRNB2 P17787 1/20 0.37
CHRM3 P20309 1/20 0.37
CHRNA4 P43681 1/20 0.37
HPGD P15428 2/20 0.37
GLA P06280 1/20 0.37
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL23466978 0.98 KDM4E (0.41) KDM4ENAAAALDH1A1GAAMGAM
SCHEMBL27416629 0.82 CA12 (0.38) NAAAALDH1A1GAAMGAMSI
SCHEMBL27787089 0.82 GAA (0.65) KDM4EALDH1A1GAAMGAMSI
SCHEMBL7573684 0.79 ALDH1A1 (0.39) KDM4EALDH1A1GAAMGAMSI
SCHEMBL11418321 0.79 KDM4E (0.38) KDM4EALDH1A1GAAMGAMSI
SCHEMBL13042034 0.79 LMNA (0.44) NAAAALDH1A1GAAMGAMSI
SCHEMBL10260866 0.77 NAAA (0.47) KDM4ENAAAALDH1A1GAAMGAM
Hydrochloric Acid SCHEMBL8094881 0.77 LMNA (0.43) NAAAALDH1A1GAAMGAMSI
Hydrochloric Acid SCHEMBL8081237 0.77 LMNA (0.43) NAAAALDH1A1GAAMGAMSI
SCHEMBL15605569 0.76 ALDH1A1 (0.62) KDM4EALDH1A1GAAMGAMSI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104725397-A Thienopyrimidine derivatives, a process for their preparation and pharmaceutical compositions containing them SERVIER LAB 2015-06-24 CN claimed
CN-116568676-A IL-17A modulators 赛诺菲 2023-08-08 CN disclosed
CN-116547275-A IL-17A modulators 赛诺菲 2023-08-04 CN disclosed
US-20230137306-A1 VIRAL INFECTION THERAPEUTIC THE UNIVERSITY OF TOKYO (JP) 2023-05-04 US disclosed
US-20230137306-A1 VIRAL INFECTION THERAPEUTIC THE UNIVERSITY OF TOKYO (JP) 2023-05-04 US disclosed
EP-4119163-A1 VIRAL INFECTION THERAPEUTIC The University of Tokyo (JP) 2023-01-18 EP disclosed
CN-111825611-A 4(1H) -quinovone derivatives and uses thereof 中央研究院 2020-10-27 CN disclosed
CN-104725397-B Thienopyrimidine derivative, its preparation method and the Pharmaceutical composition containing them 法国施维雅药厂 2017-11-28 CN disclosed
CN-104725397-A Thienopyrimidine derivatives, a process for their preparation and pharmaceutical compositions containing them SERVIER LAB 2015-06-24 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230137306-A1 VIRAL INFECTION THERAPEUTIC TMPRSS2, TMPRSS4, SPINT2 KDM4E 3096/4885NAAA 759/4885ALDH1A1 2841/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.