Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | GBA1 | P04062 | 2/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20089110 | 0.76 | CNR2 (0.46) | ALDH1A1KMT2ALMNANPSR1TSHR | |
| SCHEMBL25855482 | 0.74 | CNR2 (0.43) | ALDH1A1KDM4EKMT2ALMNANPSR1 | |
| SCHEMBL26088188 | 0.74 | KDM4E (0.46) | ALDH1A1KDM4EPOLBALOX15HSD17B10 | |
| SCHEMBL30280743 | 0.73 | CNR2 (0.44) | ALDH1A1KMT2ALMNANPSR1TSHR | |
| SCHEMBL12488177 | 0.73 | CNR2 (0.44) | ALDH1A1KMT2ALMNANPSR1TSHR | |
| SCHEMBL21262379 | 0.71 | AR (0.44) | ALDH1A1KMT2ALMNANPSR1TSHR | |
| SCHEMBL17774955 | 0.71 | HSD11B1 (0.51) | ALDH1A1HPGDKDM4EPOLBHSD17B10 | |
| SCHEMBL17774959 | 0.71 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4EPOLBHSD17B10 | |
| SCHEMBL25958653 | 0.70 | ALDH1A1 (0.42) | ALDH1A1HPGDKDM4EHSD11B1MEN1 | |
| SCHEMBL3899784 | 0.70 | L3MBTL3 (0.54) | ALDH1A1HPGDKDM4EPOLBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242404-A1 | PHENOXYPROPANOLAMINES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI-SYNTHELABO (FR) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001044227-A1 | PHENOXYPROPANOLAMINES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI-SYNTHELABO (FR) | 2001-06-21 | — | — | WO | disclosed |