Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | RRM1 | P23921 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | PTGES2 | Q9H7Z7 | 4/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | ACLY | P53396 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573951 | 1.00 | NPSR1 (0.59) | NPSR1RRM1KMT2AMEN1GAA | |
| SCHEMBL7578595 | 0.88 | NPSR1 (0.72) | NPSR1KMT2AMEN1GAAHIF1A | |
| SCHEMBL7572561 | 0.80 | NPSR1 (0.66) | NPSR1KMT2AMEN1GAAHIF1A | |
| SCHEMBL7567314 | 0.79 | NPSR1 (0.59) | NPSR1KMT2AMEN1GAAACLY | |
| SCHEMBL7572374 | 0.78 | NPSR1 (0.58) | NPSR1KMT2AMEN1GAAHIF1A | |
| SCHEMBL7570517 | 0.76 | CYP2C9 (0.61) | NPSR1KMT2AMEN1GAAMAPT | |
| SCHEMBL2828816 | 0.74 | NPSR1 (0.59) | NPSR1KMT2AMEN1GAAHIF1A | |
| SCHEMBL17978539 | 0.72 | NPSR1 (0.56) | NPSR1KMT2AMEN1GAAHIF1A | |
| SCHEMBL395600 | 0.71 | HIF1A (0.61) | NPSR1KMT2AMEN1GAAHIF1A | |
| SCHEMBL2828302 | 0.71 | SMN1; SMN2 (0.61) | NPSR1KMT2AMEN1GAAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |