SCHEMBL7574070

SCHEMBL7574070

O=C(O)C1=C(C(=O)O)C(=O)C(=O)C=C1

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 1/20 0.31
FGFR2 P21802 1/20 0.31
FGFR4 P22455 1/20 0.31
FGFR3 P22607 1/20 0.31
PTPRC P08575 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28857256 0.73 NSD2 (0.36) FGFR1FGFR2FGFR4FGFR3
SCHEMBL899101 0.65 AURKA (0.35)
SCHEMBL580338 0.64
SCHEMBL11408360 0.63 ALDH1A1 (0.32)
SCHEMBL1290379 0.63 FGFR1 (0.37) FGFR1FGFR2FGFR4FGFR3
SCHEMBL9635649 0.58 CA1 (0.40) FGFR1FGFR2FGFR4FGFR3
SCHEMBL514533 0.56 TSHR (0.35)
SCHEMBL514534 0.56 TSHR (0.35)
SCHEMBL4443898 0.55 CDC25B (0.39) PTPRC
SCHEMBL9045953 0.55 FGFR1 (0.34) FGFR1FGFR2FGFR4FGFR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0842987-B1 Incorporation of quinacridone additives during quinacridone preparation BAYER AG (US) 2002-09-04 EP disclosed
US-5755873-A Incorporation of quinacridone additives during quinacridone preparation BAYER CORPORATION (US) 1998-05-26 US disclosed
EP-0842987-A2 Incorporation of quinacridone additives during quinacridone preparation Bayer Corporation (US) 1998-05-20 EP disclosed