Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL514534 | 1.00 | TSHR (0.35) | TSHRTP53DAONAPRTALDH1A1 | |
| SCHEMBL31295488 | 0.81 | TSHR (0.40) | TSHRALDH1A1ALOX15 | |
| SCHEMBL27230432 | 0.79 | ALDH1A1 (0.35) | TSHRTP53DAOALDH1A1SRD5A2 | |
| SCHEMBL6285742 | 0.74 | — | — | |
| SCHEMBL27286767 | 0.70 | PYGM (0.39) | — | |
| SCHEMBL3412825 | 0.67 | TP53 (0.30) | TSHRTP53 | |
| SCHEMBL15330778 | 0.67 | TP53 (0.30) | TSHRTP53 | |
| Benzoic Acid SCHEMBL20185679 | 0.67 | — | — | |
| SCHEMBL27726148 | 0.67 | — | — | |
| SCHEMBL27209675 | 0.65 | TSHR (0.33) | TSHRTP53DAONAPRTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9849196-B2 | Methods and compositions for altering photophysical properties of fluorophores via proximal quenching | CORNELL UNIVERSITY (US) | 2017-12-26 | — | — | US | disclosed |
| US-9631096-B2 | Dye compositions, methods of preparation, conjugates thereof, and methods of use | CORNELL UNIVERSITY (US) | 2017-04-25 | — | — | US | disclosed |
| US-20150328340-A1 | METHODS AND COMPOSITIONS FOR ALTERING PHOTOPHYSICAL PROPERTIES OF FLUOROPHORES VIA PROXIMAL QUENCHING | CORNELL UNIVERSITY (US) | 2015-11-19 | — | — | US | disclosed |
| US-8945515-B2 | Methods and compositions for altering photophysical properties of fluorophores via proximal quenching | CORNELL UNIVERSITY (US) | 2015-02-03 | — | — | US | disclosed |
| US-20150011731-A1 | DYE COMPOSITIONS, METHODS OF PREPARATION, CONJUGATES THEREOF, AND METHODS OF USE | CORNELL UNIVERSITY (US) | 2015-01-08 | — | — | US | disclosed |
| US-8445572-B2 | Rubber composition | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2013-05-21 | — | — | US | disclosed |
| CN-101755003-B | Rubber composition | YOKOHAMA RUBBER CO LTD | 2013-03-06 | — | — | CN | disclosed |
| US-20120027689-A1 | METHODS AND COMPOSITIONS FOR ALTERING PHOTOPHYSICAL PROPERITES OF FLUOROPHORES VIA PROXIMAL QUENCHING | CORNELL UNIVERSITY (US) | 2012-02-02 | — | — | US | disclosed |
| US-20100222478-A1 | RUBBER COMPOSITION | THE YOKOHAMA RUBBER CO., LTD (JP) | 2010-09-02 | — | — | US | disclosed |
| WO-2010096720-A2 | METHODS AND COMPOSITIONS FOR ALTERING PHOTOPHYSICAL PROPERTIES OF FLUOROPHORES VIA PROXIMAL QUENCHING | CORNELL UNIVERSITY (US) | 2010-08-26 | — | — | WO | disclosed |
| CN-101755003-A | Rubber composition | YOKOHAMA RUBBER CO LTD | 2010-06-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120027689-A1 | METHODS AND COMPOSITIONS FOR ALTERING PHOTOPHYSICAL PROPERITES OF FLUOROPHORES VIA PROXIMAL QUENCHING | APEX1, PPOX, PRDX5 | TSHR 4483/4885TP53 367/4885DAO 1135/4885 |
| US-20150328340-A1 | METHODS AND COMPOSITIONS FOR ALTERING PHOTOPHYSICAL PROPERTIES OF FLUOROPHORES VIA PROXIMAL QUENCHING | APEX1, ARFGEF1, PRDX3 | TSHR 4051/4885TP53 210/4885DAO 1188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.