Aclonifen

Aclonifen

SCHEMBL7574191

CON(C)C(=O)Nc1ccc(Oc2ccc3c(c2)OC(C)(OC)CC3(C)C)cc1.CP(=O)(O)CCC(N)C(=O)O.Nc1c([N+](=O)[O-])ccc(Oc2ccccc2)c1Cl

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
TTR P02766 1/20 0.37
ALB P02768 1/20 0.37
THRB P10828 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
GRM8 O00222 11/20 0.34
GRM4 Q14833 11/20 0.34
GRM6 O15303 5/20 0.34
NPY5R Q15761 1/20 0.32
LTA4H P09960 1/20 0.31
GRM7 Q14831 2/20 0.31
ALDH1A1 P00352 2/20 0.31
MAPT P10636 2/20 0.31
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
KDM4E B2RXH2 1/20 0.31
SIRT6 Q8N6T7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aclonifen SCHEMBL7581021 0.91 MEN1 (0.45) MEN1KMT2ATTRALBTHRB
Aclonifen SCHEMBL7581867 0.88 MEN1 (0.38) MEN1KMT2ATTRALBTHRB
Bifenox SCHEMBL7576203 0.87 TDP1 (0.45) MEN1KMT2ATTRTDP1GRM8
Aclonifen SCHEMBL7577198 0.86 MEN1 (0.36) MEN1KMT2ATTRALBTHRB
Oxyfluorfen SCHEMBL7578126 0.84 MEN1 (0.36) MEN1KMT2ATTRTDP1GRM8
Fomesafen SCHEMBL7583706 0.83 TDP1 (0.38) MEN1KMT2ATTRTDP1
Glufosinate SCHEMBL7587829 0.81
Lactofen SCHEMBL7587979 0.81 TDP1 (0.37) MEN1KMT2ATTRTDP1
Glufosinate SCHEMBL7576698 0.77 FFAR1 (0.33) THRBMAPTLMNAKDM4E
Bifenox SCHEMBL7582687 0.76 TDP1 (0.56) MEN1KMT2ATTRTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT MEN1 4274/4885KMT2A 2099/4885TTR 1945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.