Bifenox

Bifenox

SCHEMBL7582687

COC(=O)c1cc(Oc2ccc(Cl)cc2Cl)ccc1[N+](=O)[O-].CON(C)C(=O)Nc1ccc(Oc2ccc3c(c2)OC(C)(OC)CC3(C)C)cc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.56
MAPT P10636 7/20 0.41
KMT2A Q03164 6/20 0.41
MAPK1 P28482 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MEN1 O00255 5/20 0.39
PKM P14618 2/20 0.39
GAA P10253 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.37
LMNA P02545 3/20 0.37
ALDH1A1 P00352 3/20 0.37
RAB9A P51151 1/20 0.35
TTR P02766 1/20 0.35
PPOX P50336 1/20 0.35
PNLIP P16233 2/20 0.33
PLA2G1B P04054 1/20 0.33
ATG4B Q9Y4P1 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
STK39 Q9UEW8 1/20 0.33
BRAF P15056 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bifenox SCHEMBL7587112 0.92 TDP1 (0.47) TDP1MAPTKMT2AMAPK1L3MBTL1
Bifenox SCHEMBL7576203 0.90 TDP1 (0.45) TDP1MAPTKMT2AMAPK1L3MBTL1
Bifenox SCHEMBL7584806 0.89 TDP1 (0.45) TDP1MAPTKMT2AMAPK1L3MBTL1
Acifluorfen SCHEMBL7582284 0.87 KMT2A (0.54) TDP1MAPTKMT2AMEN1PKM
SCHEMBL7578167 0.85 KMT2A (0.43) TDP1MAPTKMT2AMAPK1L3MBTL1
Fomesafen SCHEMBL7585363 0.84 KMT2A (0.44) TDP1MAPTKMT2AMEN1PKM
Lactofen SCHEMBL7580953 0.84 KMT2A (0.41) TDP1MAPTKMT2AMAPK1L3MBTL1
Aclonifen SCHEMBL7581021 0.83 MEN1 (0.45) TDP1MAPTKMT2AMEN1PKM
Oxyfluorfen SCHEMBL7577041 0.82 MEN1 (0.41) TDP1MAPTKMT2AMEN1PKM
SCHEMBL29390499 0.81 MEN1 (0.43) TDP1KMT2AL3MBTL1MEN1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TDP1 1969/4885MAPT 1092/4885KMT2A 2099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.