SCHEMBL7574307

SCHEMBL7574307

C1=CCC(C2[SiH2]C2C2c3cc(-c4ccccc4)ccc3-c3ccc(-c4ccccc4)cc32)=C1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 1/20 0.30
HTR2B P41595 1/20 0.30
TMEM97 Q5BJF2 1/20 0.30
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7573521 0.81 HTR2C (0.30)
SCHEMBL7575079 0.79 HTR7 (0.31) HTR7HTR2BTMEM97SIGMAR1
SCHEMBL7579177 0.79
SCHEMBL7572519 0.77
SCHEMBL7575459 0.76 SLC6A9 (0.31)
Hydrochloric Acid SCHEMBL9171686 0.66 HTR2C (0.32) HTR2BTMEM97SIGMAR1
SCHEMBL7573529 0.66 TDP2 (0.32) HTR7HTR2BTMEM97SIGMAR1
SCHEMBL7930866 0.66 MEN1 (0.33)
SCHEMBL7733091 0.65 PARP10 (0.32)
Methane SCHEMBL6557636 0.65 HTR2C (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020019504-A1 Stereospecific; low molecular weight MITSUI CHEMICALS, INC. (JP) 2002-02-14 US disclosed
US-6342568-B1 ADDITION POLYMERIZATION OF HIGHLYS STEREOSPECIFIC AND LOW MOLECULAR WEIGHT POLYOLEFINS USING CATALYST COMPRISING CYCLOPENTADIENYL-SUBSTITUTED FLUORENE COMPOUND COMPLEXED WITH GROUP IV METAL MITSUI CHEMICALS, INC. (JP) 2002-01-29 US disclosed
EP-0955305-A1 Metallocene compound, and process for preparing polyolefin by using it Mitsui Chemicals, Inc. (JP) 1999-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019504-A1 Stereospecific; low molecular weight RPLP1, RPS4Y1, POLA1 HTR7 4004/4885HTR2B 3870/4885TMEM97 2618/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.